Fungal Exam 1 Flashcards
What are exclusions to self care for dermatophyte infections?
If symptoms not improved by end of treatment course (4 wks)
Symptoms of for dermatophyte infections
localized itching, burning, pain, infected nails may become chalky & brittle
Risk factors for Tinea unguium (onychomycosis)
include increasing age, diabetes, immunodeficiency, peripheral arterial disease, smoking
Risk factors for Candida infections
- Diabetes
- Immunodeficiency disease
- High-dose corticosteroids
- Total parenteral nutrition (TPN)
- Multiple antibiotics
- Prior fungal colonization
- Immunosuppressants
Risk factors for Invasive aspergillosis
Prolonged Neutropenia
Risk factors for Vulvovaginal candidiasis
- Sexual activity (but VVC is not an STD)
- Contraceptive use (diaphragm w/ spermicide, sponge, IUD)
- Recent antibiotic use
Risk factors for Cutaneous candidiasis
- Obesity
- Tight-fitting clothing
- Activities that promote skin-to-skin rubbing
- Incontinence
- Diabetes
- Immunosuppression
- Chronic antibiotic therapy
What makes vulvovaginal candidiasis complicated?
pregnancy, immunosuppression, uncontrolled diabetes
Therapy selection for vulvovaginal candidiasis
- Multiple topical azole preparations
- Fluconazole 150 mg PO
Duration of therapy for vulvovaginal candidiasis: uncomplicated vs. complicated
- uncomplicated: 1 to 7 day
- complicated: 10-14 days
Exclusion to self-care for vulvovaginal candidiasis
- Uncomplicated that does not improve / resolve within a few days of treatment
- Complicated
First line therapy for Cutaneous candidiasis
Antifungals
First line therapy for Vulvovaginal candidiasis
- Multiple topical azole preparations
- Fluconazole 150 mg PO
First line therapy for Candidemia
- Non-neutropenic adults: remove CVC PLUS antifungal
- Fluconazole, Echinocandin, Amphotericin B, Voriconazole, Posaconazole, Isavuconazole
First line therapy for invasive aspergillosis
Voriconazole
