Histology, Physiology, Pathology Flashcards

1
Q

epithelium of platine tonsils is…

A

squamous epi

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2
Q

epi of pharyngeal tonsils (adenoids) is…

A

ciliated pseudo stratified columnar epi > sq epi

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3
Q

way to remember epitheliums

A

where food goes= squamous epithelium

where air goes= columnar epithelium

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4
Q

how does taste occur

A

sensory receptors in taste buds > synapse with afferent nerve cells > signals conveyed via cranial nerves to gustatory areas in brain

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5
Q

what are the 3 papillae in tongue (sites of taste buds)

A

filiform, valate, foliate

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6
Q

CN VII carries taste signals from…
CN IX carries taste signals from…
CN X carries taste signals from…

A

CN VII= ant 2/3rds of tongue (chrodae tympani)
CN IX= post 1/3rd
CN X= all other areas

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7
Q

3 types of taste pathology

A

ageusia, hypogeusia, dysguesia

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8
Q

how does smell occur

A

smell enters nasal cavity > passes olfactory cleft where becomes aqueous > mucus carries to olfactory neuroepithelium > olfactory cilia pick up odourant and pass it through receptor cell where become olfactory nerve fibres > pierce the cribriform plate > enter olfactory bulbs > synapse 2nd order neurones > signal passes through olfactory tract and enters temporal lobe

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9
Q

what 4 things does the olfactory epithelium contain

A

bi-polar neurones, basal cells, support cells, duct cells (from bowman’s glands- secretes mucus)

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10
Q

what are the 4 neural olfactory systems

A

CN 1 (olfactory nerve), CN 0 (nervus terminalis), accessory olfactory system, CN V (more protective)

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11
Q

what does the odourant have to be to be smelled

A

volatile and water soluble

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12
Q

pathology of smell

A

ansomia, hyposmia, dysosmia, phantosmia

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13
Q

how does hearing occur

A

sound collected and funnelled in outer ear > hits tympanic membrane > pressure waves move the ossicles in inner ear where more energy is generated > hits oval window and stapes > cochlear apparatus receives high energy pressure waves and the perilymph/endolymph is vibrated > hair cells at organ of corti stimulated generating AP > AP travels along cochlear nerve (CN VIII branch)

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14
Q

frequency dictates _____, and amplitude dictates _____

A

pitch, intensity

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15
Q

what are the 3 components of the cochlea

A

scala tympani, scala media, scala vestibuli

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16
Q

why does the middle ear need to generate more energy

A

because it requires more energy to vibrate fluid in comparison to air molecules

17
Q

difference between inner and outer hair cells is…

A

inner: perceive sound and relay to brain
outer: modulate sound

18
Q

the Eustachian tube is physiologically closed, what muscle opens it to equalise pressure between nasopharynx and ear?

A

tensor palatini muscle (CN V3 innervation)

19
Q

what is responsible for balance

A

hair cells are responsible (kinocilium and the stereoculium- hair cells of vestibular apparatus). these move with direction of movement.

20
Q

T/F: the SC canals in vestibular apparatus provide the feeling of gravity

A

F: the utricle and the saccule (otolith organs) lend the feeling of gravity, SC canals detect movement

21
Q

what is the vestibulo-ocular reflex

A

when head moves, eyesight can remain fixed.

this is achieved by inhibiting certain intra-ocular muscles .

22
Q

what does Poiseuille’s equation and Venturi effect state?

A

as airway diameter reduces, the air resistance inc 4 fold

23
Q

what are salivary glands made up of (3 components)

A

acinar (secretes digestive enzymes), ductular (myoepithelial cells), mutinous component (glycoproteins)

24
Q

what are some ear pathologies

A

otitis media, cholestatoma, tumours (Sq cell carcinoma, basal cell carcinoma, other rare cancers e.g. vestibular schwanoma)

25
where are cholesteaomas most commonly found
superoposteriar aspect of middle ear
26
name some nose pathology
rhinitis, polyps, granulomatosis with polyangiitis, tumours
27
what cancers can EBV be risk factor to and why
nasopharyngeal carcinomas, B-cell lymphomas (Hodgkin's) as virus promotes autonomic b-cell proliferation preventing apoptosis and pro-angiogenic mechanisms
28
what are some throat pathologies
polyps, contact ulcer, tumours
29
how does HPV predispose to cancers
type 16- produced E6 and E7 which disrupt p53 and RB pathways leading to lack of apoptosis/ cellular immortality
30
some salivary gland pathology
stones (sialolithiasis), infection, tumours