Histology of the male reproductive system Flashcards
what is the role of the testes?
sperm and androgen production
what is the role of the epididymis, ductus defers, ejaculatory duct, and the urethra?
sperm transport
what is the role of the seminal vesicles, prostate gland, and the bulbourethral glands?
semen production and sperm nutrient source
what is the role of the penis?
copulatory organ with erectile tissue
what is the name of the dense connective tissue capsule surrounding the testes?
the tunica albuginea
what is the network of fibrous connective tissue that is located on the posterior side of the testes that extends from the top to the bottom of each teste?
the mediastinum testis
what is house within each lobule that the septa creates?
the seminiferous tubules
where exactly does sperm production take place in the testes?
the seminiferous tubules
what is the tunica vaginalis derived from?
the peritoneum
how can the tunica vaginalis be divided?
into an outer parietal layer that is lining the scrotum and an inner visceral layer that is covering the tunica albuginea
what are the retentions testis?
a series of tubes that relay sperm out of the efferent ductules to reach the epididymis
what are the seminiferous tubules lined with?
seminiferous epithelium
what are the 2 cell types found within the seminiferous tubules?
the Sertoli cells and the spermatogenic cells
what are the seminiferous tubules surrounded by and what is the function?
they are surrounded by connective tissue and 3-5 layers of flattened peritubular myoid cells; they create peristaltic contractions that help move the spermatozoa
what cells are found in between the seminiferous tubules?
the interstitial cells of leydig
how can the interstitial cells of leydig be described?
they are steroid-producing cells (testosterone) containing lipid droplets, mitochondria, and a well-developed sER
what are the interstitial cells of leydig accompanied by?
myoid cells and fibroblasts
what kind of epithelium makes up the seminiferous epithelium?
stratified epithelium with unusual characteristics
what kind of cells are sertoli cells?
columnar cells with extensive processes
what is the hallmark of sertoli cells?
the cyclops nucleus
what is the most immature form of spermatogenic cells?
the spermatogonia
where are spermatogonia cells found?
they rest on the basal lamina
what is the most mature form of spermatogenic cell?
spermatids
where are the spermatids found?
they are attached to the apical portion of the sertoli cells near the tubule lumen
what cell population forms the blood-testis-barrier?
sertoli cells
how is the blood-testis-barrier established?
the sertoli cells are bound by tight junctions to form the sertoli-cell-to-certoli-cell junctional complex
what does the blood-testis-barrier prevent?
the attack of the haploid sperm- it significantly decreases permeability
what is found below the blood-testis-barrier?
the basal compartment
what is the basal compartment?
an open space below the junctional barrier that is adjacent to the basement membrane but also adjacent to the circulation to the testis
what is found above the blood-testis-barrier?
the luminal compartment
what is the luminal compartment?
the compartment that is exposed to the lumen of the seminiferous tubules
once cells pass from the basal compartment to the luminal compartment, what are they protected from?
any immunological response that could occur in the circulation