Histology of the GI Tract Flashcards
What are the layers of GI tube?
- Mucosa ( epithelium, lamina propria, muscularis mocusae)
- Submucosa
- Muscularis externa (Inner circular muscle, and outer longtidunal muscle)
- Adventitia/ Sarosa
Mucous secreting cells of the Stomach are found where?
Found on the surface on the epithelium
How does cells secreting mucous appear on when stained? Identify them on the image?
Pale, because their cytoplasma is filled with mucous.
The pale top surface are single cells that produce mucous and bicarbonate
What is the classification of the epithelium in th eoesophagus?
Pluse
Label the image? identifying the mucusa, submucosa, musclaris externa, sorasa/adventitia. Also Identify epithelium, lamina propria, muscularis mocusae…ect
Stratified squamous non-keritinised epithelium
What do parietal (oxyntic) cells secrete? Identify them? describe them
Hydrochloric acid
description: large pale pink stained, with spherical nucleus
What do chief (peptic) cells secrete? identify?
Pepsinogen (precurser for pepsin, conveted into pepsin upon contact with HCL acid)
What is the classification of the epithelium in the stomach?
Simple columnar epithelium
In what layer are the gastric glands in the stomach found?
Mucosa (above muscularis mucosae)
What is unique about the Stomach Layers ? what does the gastric pits open to?
Mucosa – is folded into Rugae.
- Empithelium – is simple columnar + dipressions called gastric pits.
- The Lamina Propria —- is Gastric Glands
- Muscularis Mocusae—nothing especial (same)
Submucosa —-same
Muscularis externa
- inner most oblique
- inner circular
- outer longtidunal
Sarosa..why
***** Gastric pits open to the gastric glands*****
What is found in the mucosa of the small intestine?
Villi
Crypts of Leiberkuhn
Lymphoid aggregations (Peyer’s patches)
Where are Brunner’s glands found? Identify them on the image?
Submucosa of the duodenum
Brunner’s glands secrete alkalin substance to neuturalis the acid from the stomach
In what part of the GI tract are peyer’s patches found? identify them?
more in the Ileum, some in duodanum.
Identify the Peyer’s patch, and all other structrures in the duodanum on the Q section?
What are the classic histological feature of the ileum?
label the image
lots of payer’s patch and villi
What part of the GI tract is the following image? features?
Jejunum
Jejunum: is do not have Brunner’s gland or Peyer’s patchs ( you maight see one or payer’s patch but not alot)
Jejunum have the classic mucosa, submucosa, musclaris externa, and sarosa/ adventitia.
What part of the GI tract is the following image?
Duodenum
What part of the GI tract is the following image?
Oesophagus
What part of the GI tract is the following image?
Stomach
What are Paneth cells?
Highly secretory cells that produce and package a variety of antimicrobial proteins and peptides
What does the large intestine contain histologically?
Thick mucosa
Crypts
Mucous secreting cells
What part of the GI tract is the following? Identify the classic features?
Large intestine
features: Thick Mucosa, deep crypts, goblet cells and no villi
What are some glands of the GI tract?
Salivary glands (in head/neck bodies)
Pancreas
Liver
What is the secretory component of exocrine glands?
Acinar
What are the 3 major pairs of salivary glands?
Parotid
Submandibular
Sublinguinal
What does this histological image show?
Pancreas
What is 1?
Islet of Langerhans (no endocrine part so no acini)
What is 2?
Exocrine part of pancreas, contains pancreatic acini
What is 3?
Pancreatic duct (for exocrine part)
What does this histological image show?
Liver
What is 2?
Identify the tissue and lebel
Identify and lebel the fellowing images
Identify
In the gastric gland where can you find parietal and chief cells?
describe the Gastric glands and pits varietion in the stomach?
The space of Disse is found between endothelial cells and hepatocytes in the liver - true or false?
True
- In what ways does the structure of the mucosa in this region differ from that seen in the body of the stomach?
- Which types of secretory cells predominate in the mucosa and what is the function of their secretions?
“Endocrine cells known as G cells are scattered throughout the mucosa, but you will not be able to find them in your H&E stained section”
image shows Pyloric region of the human stomach
- In the pyloric region the mucosa has long pits and short glands, while the fundus and body haveshort pits and long glands. And in the Cardia the pits are short and glands are short.
- This pyloric region glands secrete mucous, and has G-cells which secrete gastrin. The Cardiac region glands secrete mainly mucous. The Fundus and body have plenty of parietal and chief cells.
