Histology of the endometrium Flashcards
What are the three layers of the uterus?
Endometrium
Myometrium
Perimetrium
What are the histological layers of the endometrium?
Simple columnar on surface
Large lamina propria
What does the lamina propria of the endometrium contain?
Stroma and glands
How many smooth muscle layers in myometrium?
4
What two layers is the endometrium broken down into?
Stratum functionalis
Stratum basalis
What are the two layers of the S.functionalis?
Outer compact layer
Deeper spongy layer
What are the three phases of endometrium?
Proliferative
Secretory
Menstrual
What is the blood supply of the uterus?
Uterine artery (mainly), small contribution from ovarian artery
What phase is this?
Proliferative
What hormone is proliferative phase under control of?
Outline three things that occur in proliferative phase
Increase depth of S.functionalis, regenerates form cells lining glands of S basalis
Cells around developing glands, stromal cells, proliferate
Increased length of endometrial glands (Straight, unbranched)
What is the blood supply of S.basalis
Straight arteries
What is the blood supply s.funcitonalis?
Spiral arteries
What phase is this?
Secretory phase
What occurs in secretory phase? What hormon responsible?
Progesterone
Galnds grow more than surrounding lamina propria and become coiled. Secrete glycogen.
Stroma becomes oedematous and stromal cells undergo decidulisation
What is decidualization?
Changes including
- Increased glandular epithelial secretion
- Glycogen accumulation in stromal cells
- Promotes spiral arteriole development
- Promotes oedema
What phase is this?
Menstrual phase
