Histology Flashcards
Anatomy: Basics of Histology
What’s the study of tissues?
Histology
What are tissues?
Groups of similar cells & extracellular products that carry functions
How do you classify epithelial tissue?
Number (amount) AND Shape
Define: Intercellular Junctions
close connections in membrane of lateral surfaces(side)
What are the Intercellular Junctions?
Tight Junction (Zonula Occludens), Adhering Junctions (Zonula Adherens), Desmosomes (Macula Adherens), Gap Junction
Define: Zonula Occludens
Tight Junction: Closely associated areas of two cells whose membranes join together forming a virtually impermeable barrier.
EX: digestive tract
Define: Zonula Adherens
Adhering Junctions: cell junction where cytoplasmic face is linked to the actin cytoskeleton. They can appear as bands encircling the cell (zonula adherens) or as spots of attachment to the extracellular matrix (adhesion plaques).
Define: Macula Adherens
Desmosomes: (Greek: desmos=band, soma, body) buttons between cell stress points
EX: most epithelial tissues
Define: Basal layer
Basement structure: Extracellular layer in between Epithelial basal surface and connective tissue.
Define: Avascular
no blood vessels. obtain nutrients from apical surface or by diffusion across basal
What are the 3 layers of cells distinguished by number?
simple- 1 layer
stratified- +1layer
pseudostratified- false layers
Name Cell Classifications
Squamous, Cubidol, Columnar, Transitional
Define: Endothelium
Tissue that forms a single layer of cells lining various organs and cavities of the body. It is formed from the embryonic mesoderm.
EX: blood vessels, heart, and lymphatic vessels.
Define: Mesothelium
The epithelium that lines the pleurae, peritoneum, and pericardium (primary germ layer Mesoderm)
What are Glands?
individual/multicellular organs predominantly from epithelial tissue that secrete chemical substances
Squamous Cells
“scaly” and flat
Cubidol Cells
“cube” with round nucleus in the center
Colmunar Cells
“column”; nucleus basal
Transitional Cells
morph; change due to expanding epithelial
EX: empty bladder (polyhedral cell)
What does endocrine secrete?
Hormones
Merocrine (Eccrine) Glands
(Greek: meros=share)
package secretion in secretory vesicles, release through exocytosis
eccrine glands: sweat glands not connected to hair follicles
EX: Lacrimine (tears) gland, salivary, sweat
Which gland accumulates and then disintegrates?
How does it secrete it’s chemicals?
Holocrine Glands
secretory accumulates>cell dies>breask off>cell division at base
EX: sebaceous (oil) gland
Which gland’s secretion accumulates on applicable part of cytoplasm?
Apocrine Glands
(Greek: appo=off)
EX: axial
Anatomic Classification: Simple Gland
single, unbranched duct
Anatomic Classification: Compound Gland
branched ducts
Anatomic Classification: Acinar
expanded sacs
Anatomic Classification: Tubular
uniform diameter
Anatomic Classification: Tubuloacinar
Combination of acinar and tubular
What’s the purpose of Connective Tissue?
Support, Bind, Protect
What are the Connective Tissue characteristics?
cells, ground substance (matrix), protein fibers