Histology Flashcards
What is the basic structural and functional unit of life?
Cell
What is the epithelial lining of the heart and blood vessels ?
Simple squamous
What is the epithelial lining of the serous surfaces ( pericardium, peritoneum, pleura) ?
Simple squamous
What is the epithelial lining of the colon?
Simple columnar
What is the epithelial lining of the covering of ovaries?
Simple cuboidal
What is the epithelial lining of the thyroid gland follicles?
Simple cuboidal
What is the epithelial lining of the collecting tubules of the kidney?
Simple cuboidal
What is the epithelial lining of the small intestine?
Simple columnar
What is the epithelial lining of the fallopian tubes?
Simple columnar
What is the epithelial lining of the respiratory tract?
Simple columnar
What is the epithelial lining of the vas deferens ?
Simple columnar
What are the organs with simple squamous epithelium?
- Heart
- Blood vessels
- Pericardium
- Peritoneum
- Pleura
What are the organs with simple cuboidal epithelium ?
- Covering of Ovaries
- Thyroid gland follicles
- Collecting tubules Of the Kidney
What are the organs with simple columnar epithelium?
- Colon
- Small intestine
- Fallopian Tubes
- Respiratory Tract
- Vas deferens
What are the cells that forms the myelin?
- Schwann cells
- Oligodendrocytes
Surface Ectoderm Examples (10)
- Sensory organs of the ear
- Adenohypophysis
- Lens of the eye
- Epidermis
- Epithelium of the oral cavity
- Epithelium of the anal canal below the pectinate line
- Parotid Glands
- Sweat Glands
- Mammary Glands
- Olfactory Epithelium
Neural tube from Ectoderm Examples
- Brain
- Neurohypophysis
- CNS neurons
-All CNS Glial Cells except microglia & pineal gland - Spinal cord
- Retina
Neural crest cells from ectoderm examples (10)
- Enterochromaffin cells
- Leptomeninges (arachnoid & pia mater)
- Melanocytes
- Odontoblasts
- PNS ganglia
- Adrenal Medulla
- Schwann Cells
- Spinal membrane / Aorticpulmonary Septum
- Endocardial cushions
- Skull bones
Mesoderm examples (17)
- Dermis
- Muscle
- Bone
- Connective tissue
- Tracheal cartilage
- Cardiovascular structures
- Lymphatics & Blood
- Serous lining of cavities
- Kidneys
- Adrenal cortex
- Spleen
- Wall of gut tube
- Upper 2/3 of vagina
- Testes & Ovaries
- Microglia
- Dura mater
(Microglia lumabas sa board exam)
Endoderm examples (13)
- Gut tube epithelium including anal canal above pectinate line
- Most or urethra
- Lower 1/3 of vagina
Luminal epithelium derivatives:
4. Lung
5. Liver
6. Gallbladder
7. Pancreas
8. Eustachian tube
9. Thymus
10. Parathyroid
11. Thyroid
12. Follicular cells
13. Parafollicular cells
The most common connective tissue cell that has a euchromatic nucleus and it produces ground substance and extracellular fibers.
Fibroblasts
Produces hydrochloric acid and intrinsic factors.
Parietal (Oxyntic) Cell
Connective tissue which envelopes muscles.
Epimysium
Cell that forms myelin in the CNS.
Oligodendrocytes
Most abundant type of cartilage; serves as temporary skeleton for fetus.
Hyaline cartilage
Cells that secrete osteoclast stimulating factor in the presence of PTH.
Osteoblasts
Types of Collagen fibers (6)
Type I: bONE
Type II: carTWOlage and vitreous
Type III: reTHREEculin fibers
Type IV: On the floor - Basement membrane
Type V: buntis five : Fetal Tissue & Placenta
Type VII: Connects the Basement membrane to Reticular Lamina
No type VI
Striated border that is formed by surface of osteoclast that abuts on bone.
Ruffled border
Deepest single layer of tall cuboidal keratinocytes resting on a basement membrane which consists of a well-developed basal lamina that is supported by its deep surface by a lamina fibroreticularis.
Stratum Germinativum (Stratum Basale)
Layer of the skin which is seen only in thick skin?
Stratum Lucidum
Layer of the skin where Langerhans cells are most numerous.
Stratum Spinosum
Thinnest layer of hair which consists of dead, flattened heavily keratinized cells.
Cuticle
Skin layer affected in bullous pemphigoid.
Epidermal basement membrane
Normal RBC, WBC, and platelet values.
RBC: 4.5-6 million cells / uL (456)
WBC: 4,000-10,000 / uL
Platelets: 150-450,000 / uL
Hormones produced by the stomach mucosa.
- Gastrin
- Somatostatin
- Histamine
Characteristics of platelets. (3)
- Smallest blood component seen only under the microscope.
- Formed by the fragmentation of megakaryocytes within the bone marrow.
- Once activated it forms into spherical form
Characteristic of erythrocytes. (3)
- Anucleate
- Biconcave
- 120 days lifespan
Variation in RBC shape.
Poikilocytosis
Clock face nucleus.
Plasma Cell ( Plasma Clock)
Kidney -shaped nucleus and frosted cytoplasm.
Monocyte ( Frozen Kidney Mo)
Most potent antigen presenting cell.
Dendritic cell ( potDEN antigen presenting cell)
Granulocytes (3)
- Neutrophils
- Eosinophils
- Basophils
(Grandpa BEN )
Agranulocytes (2)
- Lymphocytes
- Monocytes
(AGrand LyMo)
Pale central area where lymphocytes are proliferating.
Germinal center
Epithelial lining of the upper esophagus.
Non-keratinized Stratified Squamous Epithelium
Organ of the GIT with no submucosal layer.
Gallbladder
Largest lymphoid organ in the body.
Spleen
Hyaline cartilage seen in these region of airway.
Bronchi
Surrounds AV orifices and origin of aorta and pulmonary artery.
Annuli Fibrosa
Small blood vessels within wall of large blood vessels.
Vasa Vasorum
Glands that are confined to submucosa of duodenum and its ducts open into bottoms of Crypts Liberkuhn.
Glands of Brunner
Large aggregates of lymphoid nodules in Ileum.
Peyer’s Patches
Branched acinar glands with purely serous acini.
Parotid gland
Branched tubuloacinar glands with both serous and mucus secreting acini.
Submandibular gland
Neurons found in the brain and retina ; non spiking interneurons.
Anaxionic neurons
Aggregations of secretions seen in Neurohypophysis.
Herring bodies
Separates anterior from posterior lobe and produces melanocyte stimulating hormone.
Pars Intermedia
Spermatogenesis occurs in _______________.
Seminiferous tubules of testes
Layer that regenerates after menstruation.
Basal layer
Blind spot of retina.
Optic disc
Atea with complete absence of rods & cones.
Optic disc
Cells responsible for forming tight occluding junctions in the blood testis barrier.
Sertoli cells
Part of the fallopian tube with numerous mucosal folding.
Ampulla
Epidermal appendages. (4)
- Hair
- Nail
- Sweat glands
- Sebaceous gland
Releases glucocorticoids (3)
- Zona fasciculata
- Zona glomerulosa
- Zona reticularis : Androgens
Differentiate squamous cell & basal cell carcinoma.
- Both are caused by sun damage.
- Both arise from the epidermis.
- BCCa- rare metastasis
- SCCa- can metastasize
Secretes mineralocorticoids.
Zona glomerulosa
Adrenal medulla origin.
Neural crest cells