Histology Flashcards
tissue level
groups of similar cells and extracellular products that carry out a common function
histology
study of normal tissue
pathology
study of diseased tissue
extracellular matrix
non living material that cells secrete, surrounds,m and binds cells composition: liquid “plasma” semisolid “cartilage” solid “bone”
4 basic tissues
epithelial, connective, muscle, and nervous
epithelial tissue
covers body surface, lines body cavities lumens and glands form
epi= upon; thelium= to cover
connective tissue (C.T.)
bind, supports and protects body parts
location of epithelial tissue
covers the bodys surface, is part of the serous membranes that line body cavities, lines the lumen of tubes and ducts and forms glands
(one side exposed to a body cavity, lumen, skin)
polarity of epithelial tissue
apical surface, lateral surface, basement membrane and basal surface
apical surface
faces lumen
lateral surface
sides
basal surface
part connected to C.T.
basement membrane
connect epithelial tissue to connective; acts as a filter
cellularity of epithelial tissue
the cells are tightly packed, have specific types of junctions, and have very little extracellular matrix
intercellular junctions
between epithelial cells
- tight junction
- adhering junction
- desmosome
- gap junction
tight junction
close to apilical border; border around lateral sides to prevent material from going between cells
adhering junction
strengthen material going through cells
gap junction
electrical junction, cells can communicate rapidly
attachment of epithelial tissue
basal surface is attached to C.T. by a thin membrane
parts of it are made by epithelium and parts by C.T.
it anchors epithelium, strengthens the attachment to the C.T.
forms a selective molecular barrier to regulate the movement of large molecules between the epithelium and C.T.
Avascular
doesnt have blood vessels, have to get nourishment from C.T. below it
high regeneration (mitotic) capacity
divide rapidly epithelial tissue regenerates
functions of epithelial tissue
physical protection, selectively permeability, secretions, and sensations
physical protection
epithelium, compartmentalize, control, permeability (must cross abs filtr diffusion)
classification of epithelial tissue
number of cell layers
simple, stratified, and pseudostratified
simple
has a single layer, every cell in contact with basement membrane
function: filtration, diffusion, osmosis
stratified
more than one layer
function; protection (anus, vagina, oral cavity)
pseudostratified
false, every cell in contact with basement membrane
classification of epithelial tissue
cell shape at apical surface
squamous, cuboid, columnar, and transitional
squamous
very thin, all capillaries
cuboid
square cell, in center
columnar
tall cells
specializations on apical surface of epithelial tissue
microvilli, cilia, stereocilia, and metaplasia
microvilli
tiny, cytoplasmic projections on the apical surface. the function of microvilli (brush border) is to increase the surface area for secretion and absorption through the apical surface
ex) digestive tract
cilia
hair like projections on the apical surface that move substances across the apical surface
ex) in uterine tubes and respiratory tract
stereocilia
are long, stiff microvilli on hair cells of the inner ear for equilibrium and hearing
metaplasia
changing from one cell type to another
types of epithelium
simple squamous, simple cuboid, simple columnar, stratified squamous, pseudostratified, stratified cuboidal, stratified columnar, and transitional
simple squamous
single thin layer of flat cells. the function is for diffusion, osmosis and filtration. it has different names in different places (alveoli and lungs)
- endothelium
- mesothelium
endothelium
lines the inside of the heart chambers (aka endocardium), lines the inside of blood and lymphatic vessels and is the capillary wall
mesothelium
part of the serous membranes that line the ventral body cavity and the organs in those cavities: pleura, pericardium, and peritoneum
simple cuboidal
single layer of cells as wide as they are tall. the function is to absorption and secretion. simple cuboid lines small ducts and tubes.
ex) much of nephron tubules for reabsorption of glucose, ions, and water