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zABSITE 2019 - high yield comprehensive > High Yield COPY > Flashcards

High Yield COPY Flashcards

1
Q

Fibrin

A

Links Gp2b/3a to form PLT plug

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2
Q

Thrombin functions

A
  1. Fibrinogen to fibrin
  2. Activates f5, 8
  3. Activates PLTS
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3
Q

AT3 Functions

A
  1. Inhibits thrombin

2. Inhibits f9, 10, 11

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4
Q

Plasmin

A

Degrades f5, 8, fibrinogen, and fibrin

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5
Q

TXA2

A

Released from PLT
Ca release exposes Gp2b/3a
Increases PLT aggregation and promotes constriction

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6
Q

Cryo

A

vWF, f8, fibrinogen

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7
Q

FFP

A

All factors, Protein C and S, AT3

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8
Q

DDAVP

A

Cause endothelium to release f8 and vWF

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9
Q

Clopidogrel

A

MOA: ADP receptor (gp2b/3a) antagonist

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10
Q

Aminocaproic acid

A

Plasmin inhibitor

Use: DIC, excess tpa

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11
Q

Warfarin reversal

A
  1. Emergent: PCC or f7a (more s/e)

2. Oral K

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12
Q

Anti-staph Penicillins

A

Oxacillin
Methicillin
Nafcillin

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13
Q

Beta lactamase inhibitors

A

Sulbactam
Clavulanic acid
Tazobactam

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14
Q

Effective for enteroccous

A 
Ampicillin
Amoxacillin
Vancomycin
Timentin
Zosyn
***resistant to all cephalosporins
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15
Q

Effective for P/A/S

A 
Ticarcillin, Piperacillin, Timentin
Zosyn
3G cephalosporin
Aminoglycodies (genta, tobra)
Meropenem, Imipenem
Flouroquinolones
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16
Q

Effective for VRE

A

Synercid

LInezolid

17
Q

P450 inducers

A 
Cruciform vegetables
ETOH
Cigarette smoke
Phenobarb
Barbiturates
Dilantin
Theophylline
Warfarin
18
Q

P450 inhibitors

A 
Cimetidine
Isoniazid
Ketoconazole
Erythromycin
Cipro
Flagyl
Allopurinol
Verapamil
Amiodarons
MAOi
Disulfuram
19
Q

Halothane

A

Slow onset/offset. Least pungent (children)
s/e:
- highest cards depression and arrhythmia
- halothane hepatitis
- avoid w/ neurosurg

20
Q

Sevoflurane

A

fast, less laryngospasm, less pungent

good for mask induction

21
Q

Isoflurane

A

Good for neurosurgery

Pungent (not used for induction)

22
Q

Propofol

A

Rapid distribution and on/off
s/e- hypotension, resp depression, meta acid
metabolism- liver

23
Q

Ketamine

A

No respiratory depression
s/e
- hallucination, catelcholamine release, airway secretions, increased CBF
- c/i in head injury

24
Q

Etomidate

A 
Fewer hemodynamic changes
Fast acting
Fewest cards s/e
s/e
- adrenocortical suppresion w/ cont infusion
25
Q

Dexmedetomidine

A 
Mech- CNS alpha2 ago
Not an induction agent. Good for intubated pts
Anesthesia and analgesia
s/e
- not for more than 24h
26
Q

Depolarizing agents

A

Succinyl choice
Malignant hyperthermia
Hyperkalemia
Glaucoma

27
Q

Ca EKG

A

HyperCA- Short ST, wide T

HypoCA- long QT

28
Q

HypoMg EKG

A

Tall t waves

Depressed ST

29
Q

K ECG

A

HyperK- Peaked T, wide QRS, long PR

HypoK - ST depression, inverted T

zABSITE 2019 - high yield comprehensive (12 decks)

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