3. Blood Products

Question 1

CMV negative blood

Answer 1

Use in low BW infants

Transplant patients

Question 2

1 6 pack of PLT should raise PLT by

Answer 2

50k

Question 3

Acute Hemolysis Reaction

Answer 3

Mech: ABO incompatibility. T2 HS reaction.
Dx: Hapto < 50, free Hb > 5, increase uBili
Tx: fluids, diuretics

Question 4

Electrolytes after transfusion

Answer 4

1. HypoCa: citrate chelation
2. Alkalosis: citrate degrades to bicarb
3. HyperK: stored cell lysis

Question 5

Febrile nonhemolytic transfusion reaction

Answer 5

Mech: recipeint Ab against donor WBC
Tx: dc trx. Use WBC filter for subsequent trx.

Question 6

Anaphylaxis

Answer 6

Mech: recipient Ab against donor IgA
Px: emergent airway
Tx: epinephrine

Question 7

TRALI

Answer 7

Mech: donor Ab to recipient’s WBC
Px: clot in pulmonary capillaries, ARDS

Question 8

Most common CO death with transfusion

Answer 8

1. TRALI (although rare)
2. ABO incompatability
3. Infection

Question 9

MC bacterial contaminate and source

Answer 9

GNRs (e. coli, pseudomonas) from PLTs