HEV_High_Yield_Flashcards
What is an alternative name for Hepatitis E Virus (HEV)?
Norwalk virus.
What is the genome type of HEV?
Linear positive-sense single-stranded RNA (ssRNA) genome, 7.2 kb.
What is the structure of HEV?
Icosahedral and non-enveloped structure.
How is HEV transmitted?
Fecal-oral route, often waterborne transmission.
What is the incubation period for HEV?
48 hours.
What are the general characteristics of HEV disease?
Generally self-limiting but more severe in pregnant women.
Why is HEV particularly severe in pregnant women?
HEV in pregnant women can cause fulminant hepatic failure with high mortality.
What are the symptoms of HEV?
Symptoms are similar to HBV but less severe, and include viral gastroenteritis.
Does HEV lead to chronic infection?
No, HEV does not cause chronic infection.
Where is HEV commonly found epidemiologically?
HEV is common in developing countries and linked to waterborne outbreaks and epidemic gastroenteritis.
What tests are used for the diagnosis of HEV?
Serological tests detect HEV antibodies, and PCR detects viral RNA in stool samples.
What is the role of PCR in HEV diagnosis?
PCR detects HEV RNA in stool samples and confirms active infection.
How is HEV treated?
Treatment is symptom-based as there is no specific therapy.
Is there a vaccine for HEV?
No, there is no vaccine for HEV.
What are the preventive measures for HEV?
Good hand washing, improved sanitation, and use of disinfectants to prevent waterborne outbreaks.
