Heritability and Intelligence Flashcards
• To consider what heritability is and what this means in the context of intelligence • To explore the complex genetic and environmental factors that contribute to intelligence To evaluate the misuse of heritability in intelligence testing & research and the negative impact this has had more recently
what are the main 2 case study considerations we’re looking at?
- importance of critical thinking in research
- importance of community in research and the need for this to be diverse
first-degree relative
share ~50% of genes i.e. parents and siblings
second-degree relative
share ~24% of genes i.e. grandparents, grandchildren, aunts, uncles, niblings
third-degree relative
share ~12.5% of genes i.e. great grandparents, great-aunt, great-uncle, first cousins
genotype
genetic make-up of an individual
phenotype
individual’s observable traits i.e. height, eye colour, blood type and intelligence
who is Francis Galton?
- first introduced nature vs. nurture (believed it was heritable but acknowledge environmental factors that may impact it) -> first to consider heritability in relation to Darwin
- started looking at familial relations and its connection to ‘eminence
- moved on to consider role of environment -> surveying total society members to explore the role of nature vs. nurture (looking at upbringing, education and opportunity on their success)
- suggested key methodology for looking at heritability -> i.e. twin and family adoption studies
what is eminence (and the familial connection)?
people who hade done really successful things -> looking at family relations and whether the second-related individual was more eminence than others and whether that decreased as the degree of relation goes down -> genetic link to intelligence?
what do we mean by genetic heritability?
- genotype is biologically transmitted from their two parents (50% from each)
- the genotype influences the phenotype
* this is genetic heritability -> variability between parents and child / the proportion of shared variance of the genotype that’s influencing the genotype (how much of the genotype actually influences the genotype) - child phenotype
what happens when the proportion of shared variance is low?
parent and child are quite different
* variability is high
what happens when the proportion of shared variance is high?
parent and child are very similar
* variability is low
what phenotypes are entirely genetic?
physical characteristics particularly i.e. having a nose / eye colour are entirely genetic and determined by your genotype
what about phenotypes that aren’t entirely genetic?
environment may play a role in the child’s phenotype, altering how genes are expressed i.e. intelligence
what do we mean by heritability?
- genes biologically transmitted from parent to child -> 50% from each parent
- how much of the phenotype i.e. intelligence is passed from parent to child is genetic heritability
how is genetic heritability assessed?
considering the variability found between parents (how much they differ) and in terms of proportion of shared variance (how much they are the same)
* presented as a %
what are the two (broad) techniques, we can look at when looking at heritability estimates?
behavioural approaches and DNA / physiological approaches
what is behavioural genetics?
the average estimate of the proportion of variance for intelligence thought be accounted for by genetic factors across a population
- interest in estimating genetic heritability across populations
- expressing it in terms of shared variance
why are we estimating for a population?
estimates says nothing about an individual -> cannot tell a person what a proportion of their genes are contributing to their intelligence
* estimate because we can’t control for all factors
what are three ways we can assess genetic hertiability?
family studies, twin studies and adoption studies
*these give natural occurrences in different groups which we can compare that differ levels in terms of shared genetic makeup and shared environment / or not shared environment
* started to tease apart how much genes influence and how much environment influences phenotype
family studies
- parents-children share ~50% of genes
- can consider the associations here
- similarities may be due to shared environment
twin studies
- identical (MZ) share 100% of the same genes
- non-identical (fraternal, DZ) share 50% of the same genes
- can compare (with non-twins) the influence of genetics
adoption studies
- consider the role of genes and environment
- parents / adopted child
- twins or siblings raised apart
how do these studies assess for genetic heritability?
NOT physiological
- look for similarties / differences in intelligence through observations, interviews, questionnaire and intelligence test measures
what do we need to consider when using heritability estimates?
- they are just estimates
- do not refer to estimates for an individual -> estimates of the average heritability among a certain population of people instead
what do heritability estimates actually tell us?
as we reduce the level of shared genetic makeup, we get less shared variance -> suggestion of a environment contribution almost
by the 80s, there was a general idea that the genetic heritability of intelligence fell between…
40-80%
what is the percentage of genetic heritability estimates Eysenck (1979) gave?
69%
what is the percentage of genetic heritability estimates the Bell Curve gave?
74%
genome-wide association study
considers the entire set of DNA of a large group of people -> searching for small variations in a wide pool of DNA
single nucleotide polymorphism (SNP or ‘snips’)
small variations being searched for in the genome wide association studies
what is the use of SNPs?
sciences can look for 1000s of SNPs and potentially identify SNPs that occur more frequently in people with a certain disease or trait (scoring more highly or low on certain tests)
Deary looked at genetic heritability of a person’s stability of intelligence across their life span (1932 and 1998).
What did he find?
slight increase in intelligence (age-related) and was quite stable (r ~.60)
Deary et al. (2012) investigated the genetic contribution to stability of intelligence across the lifespan in 1940 unrelated individuals. He measured intelligence at 11 year olds and then at 65, 70 or 79 years old -> combing this with a DNA analysis. He examined over half a million genetic markers to see how genetically similar these individuals were despite not being related
What did he find?
genetic contribution to the stability of intelligence across the life span but it’s a lot lower than what we found in family / twin studies (38%)
Dear (2012) conducted a meta-analysis around heritability estimates of intelligence in different cultures. what did he find?
when considering the genetic contribution to intelligence stability across many studies, Deary found that it varied across life span and across cultures
Davies et al., (2011) directly considered the heritability of intelligence using
* genome-wide data looking for SNPs
* phenotype data (measures of cognitive traits associated with intelligence
Compared 3511 unrelated, middle to older adults
What did they find?
40%-50% of the variation in human intelligence is associated common SNPs