hereditary angioedema Flashcards
1
Q
non pruritic lip swelling
positive family history
A
hereditary angioedema
see deficient in C1 inhibitor protein
2
Q
what does C1 inhibitor do?
A
it helps inhibit excessive bradykinin production
unchecked excessive amount of bradykinin can lead to angioedema involving the faical area as well as larynx and GI distress
3
Q
diagnosis of hereditary angioedema is
A
lab testing for decreased C1 inhibitor protein
4
Q
Treatment of hereditary angioedema
A
C1INH concentrate icatibant (a bradykinin B2 receptor antagonist or ecallantide (a kallikrein inhibitor that blocks bradykinin)
