HEPATOBILIARY Flashcards
When Jaundiced in hepatitis, what is liver ALT levels?
super high in the 1000s
what causes high ALT?
hepatocyte membrane damage
When do you get Mallory bodies?
alcoholic hepatitis
when do you get centrilobular necrosis?
paracetomol toxicity
what is a Councilman body?
hepatocyte undergoing apoptosis
2 giveaways of alcoholic hepatitis?
Mallory bodies
Neutrophils
Cholestasis histologically see?
yellow brown dots (bile plug) in dilated biliary canaliculi
what is a hallmark feature of acute viral hepatitis B?
APOPTOSIS and ground glass hepatocytes
what happens to portal tracts in chronic hepatitis C? 4 things
- lymphocytes infiltration
- Fatty change
- interface hepatitis
- bridging fibrosis
Two examples of Non-alcoholic fatty liver disease?
DM and CHF
What is steatosis?
just fat (triglyceride) in the liver fatty liver
3 types of steatosis are?
macrovesicular/large droplet
microvesicular/small droplet
Mixed type
Liver failure skin findings
Erythema, spider angioma, jaundice
Rusty smell in liver failure
mercaptans
Renal failure in liver failure
Hepatorenal syndrome