hepatitis virus Flashcards
1
Q
what do hepatitis viruses specifically target and what do they infect
A
liver, hepatocytes
2
Q
subfamily
- HAV
- HBV
- HCV
- HDV
- HEV
A
- picornaviridae
- hepadnaviridae
- flaviviridae
- deltaviridae
- calciviridae
3
Q
genome
- HAV
- HBV
- HCV
- HDV
- HEV
A
- +ssRNA
- circ ds DNA
- +ssRNA
- -ssRNA
- +ssRNA
4
Q
enveloped/non
- HAV
- HBV
- HCV
- HDV
- HEV
A
- non
- env
- env
- env
- non
5
Q
transmission
- HAV
- HBV
- HCV
- HDV
- HEV
A
- fecal-oral, sex, parenteral
- sex, vertical, parenteral
- sex, vertical, parenteral
- sex, vertical, parenteral
- fecal-oral, sex, parenteral
6
Q
which types of herpes virus are very rare in the US
A
HDV and HEV
7
Q
can HBV be grown in culture
A
no
8
Q
what is HBV template for transcription
A
cccDNA
9
Q
incub per for HBV
A
30-180 days
10
Q
recovery from HBV
A
3-4 months after jaundice
11
Q
is HBV chronic?
A
in 5 % cases
12
Q
vaccine for HBV
A
yes, need multiple innoculations
13
Q
Tx for HBV
A
IFN alpha, nucleoside analogs (adefovir, lamivudine, tenofovir)
14
Q
what is HDV and what does it require
A
a subviral agent that requires an active HBV infection
15
Q
proteins in HCV
A
E1 and 2, C, other non structurals
