hemonc Flashcards
normocytic anemias
anemia of chronic disease
macrocytic anemias
hemolysis, folate/B12 deficiency,
microcytic anemias
thalassemias, iron deficiency
low transferrin, low serum iron, low serum transferrin receptor, low TIBC
anemia of chronic disease
aregenerative anemia (cells show central pallor)
iron deficiency anemia
jaundice, gallstones, pallor, decreased o2 delivery
hemolytic anemia
increased retic count in the presence of falling or stable hematocrit
hemolytic anemia
immature re cells, nucleated red cells on peripheral smear
hemolytic anemia
pancytopenia with circulating blasts
acute leukemia (must have 20% blasts on Bone marrow biopsy)
ALL
children.
auer rods
AML
leukemia with smudge cells, isolated lympocytosis with leukocytosis >20,000
CLL
philadelphia chromosome
CML
Gleevec is the tx for what leukemia?
CML
ITP sxs
hemorrhage, nosebleedins, bruising, gingival bleeding when platelets are less than 20-30K
tx ITP
corticosteroids and transfusions
TTP tx
immediate administration of plasma exchange
what is TTP?
thrombocytopenia due to incorporation on platelets into thrombi in microvasculature leading to microangiopathic hemolytic anemia
labs TTP
elevated LD, indirect bilirubin. decreased haptoglobin, schistocytes (all related to hemolysis)
Hodgkins lymphoma treatment
chemo plus ABVD (adriamycin, bleomycin, vinblastine, decarbazine)
reed sternberg cells
hodgkins lympoma
polycythemia
disease state in which the proportion of blood volume that is occupied by red blood cells increases. Blood volume proportions can be measured as hematocrit level. It can be due to an increase in the number of red blood cells[
sxs polycythemia
reddened face, bleeding of the gums, dizziness, and itchiness, blurred vision or tinnitus. In more serious cases of polycythemia, thrombosis (clotting) can develop, leading to heart attack or stroke.
tx polycythemia
oxygen
