hemonc Flashcards

1
Q

normocytic anemias

A

anemia of chronic disease

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2
Q

macrocytic anemias

A

hemolysis, folate/B12 deficiency,

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3
Q

microcytic anemias

A

thalassemias, iron deficiency

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4
Q

low transferrin, low serum iron, low serum transferrin receptor, low TIBC

A

anemia of chronic disease

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5
Q

aregenerative anemia (cells show central pallor)

A

iron deficiency anemia

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6
Q

jaundice, gallstones, pallor, decreased o2 delivery

A

hemolytic anemia

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7
Q

increased retic count in the presence of falling or stable hematocrit

A

hemolytic anemia

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8
Q

immature re cells, nucleated red cells on peripheral smear

A

hemolytic anemia

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9
Q

pancytopenia with circulating blasts

A

acute leukemia (must have 20% blasts on Bone marrow biopsy)

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10
Q

ALL

A

children.

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11
Q

auer rods

A

AML

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12
Q

leukemia with smudge cells, isolated lympocytosis with leukocytosis >20,000

A

CLL

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13
Q

philadelphia chromosome

A

CML

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14
Q

Gleevec is the tx for what leukemia?

A

CML

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15
Q

ITP sxs

A

hemorrhage, nosebleedins, bruising, gingival bleeding when platelets are less than 20-30K

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16
Q

tx ITP

A

corticosteroids and transfusions

17
Q

TTP tx

A

immediate administration of plasma exchange

18
Q

what is TTP?

A

thrombocytopenia due to incorporation on platelets into thrombi in microvasculature leading to microangiopathic hemolytic anemia

19
Q

labs TTP

A

elevated LD, indirect bilirubin. decreased haptoglobin, schistocytes (all related to hemolysis)

20
Q

Hodgkins lymphoma treatment

A

chemo plus ABVD (adriamycin, bleomycin, vinblastine, decarbazine)

21
Q

reed sternberg cells

A

hodgkins lympoma

22
Q

polycythemia

A

disease state in which the proportion of blood volume that is occupied by red blood cells increases. Blood volume proportions can be measured as hematocrit level. It can be due to an increase in the number of red blood cells[

23
Q

sxs polycythemia

A

reddened face, bleeding of the gums, dizziness, and itchiness, blurred vision or tinnitus. In more serious cases of polycythemia, thrombosis (clotting) can develop, leading to heart attack or stroke.

24
Q

tx polycythemia

A

oxygen

25
Q

tx of von willebrand disease

A

desmopressin (DDAVP)

26
Q

heinz bodies

A

thalassemia, G6PD or postsplenectomy

27
Q

4 causes of microcytic anemia

A

TICS: thalassemia, iron deficiency, chronic disease, sideroblastic