HEMOFLAGELLATES Flashcards

1
Q

Leishamania spp.

MOT / INFECTIVE STAGE:
VECTOR:
DIAGNOSTIC STAGE:

A

MOT / INFECTIVE STAGE: Promastigotes

VECTOR: Sandflies

DIAGNOSTIC STAGE: Amastigotes

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2
Q

Trypanosoma brucei complex

MOT / INFECTIVE STAGE:
VECTOR:
DIAGNOSTIC STAGE:

A

MOT / INFECTIVE STAGE: metacystic / metacyclic TRYPOMASTIGOTES

VECTOR: Tsetse flies (Glossina)

DIAGNOSTIC STAGE: Trypomastigotes (extracellular)

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3
Q

Trypanosoma cruzi

MOT / INFECTIVE STAGE:
VECTOR:
DIAGNOSTIC STAGE:

A

MOT / INFECTIVE STAGE: metacystic / metacyclic TRYPOMASTIGOTES

VECTOR: Kissing bug (Reduviid / Triatomine bug)

DIAGNOSTIC STAGE: AMAStigote & TRYPOmastigote

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4
Q

Developmental Stages “PAMET”

A

Promastigote
Amastigote
Metacystic Trypomastigote
Epimastigote
Trypomastigote

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5
Q

Developmental Stages “PA” of Leishmania spp

A

Promastigote
Amastigote

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6
Q

Developmental Stages “MET” of T. brucei complex

A

Metacystic Trypomastigote
Epimastigote
Trypomastigote

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7
Q

Developmental Stages “AMET” of T. cruzi

A

Amastigote
Metacystic Trypomastigote
Epimastigote
Trypomastigote

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8
Q

Skin lesions with elevated margins that leave ugly scars on healing

A

Cutaneous Leishmaniasis

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9
Q

Highly disfiguring, leprosy-like cutaneous lesions that spread to the mucous membranes

A

Muco-cutaneous Leishmaniasis

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10
Q

Fever, organomegaly, ascites, anemia, hyperpigmentation of the skin

A

Visceral Leishmaniasis

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11
Q

Trypanosome chancre
Hemolymphatic stage – fever and cervical lymphadenopathy called WINTERBOTTOM SIGN

A

West African Trypanosomiasis

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12
Q

Meningoencephalitic or sleeping stage– somnolence, coma, and death

A

East African Trypanosomiasis

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13
Q

2 Lesions at inoculation site of American Trypanosomiasis:

  1. swelling around the eye / orbital edema
  2. swelling at the other site / bite site
A
  1. Romaña
  2. Chagoma
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14
Q

Cutaneous Leishmaniasis Agents

Old Wold CL:
New World CL:

A

Old Wold CL: L. tropica

New World CL: L. mexicana

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15
Q

Muco-cutaneous Leishmaniasis Agents

A

L. braziliensis

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16
Q

Visceral Leishmaniasis Agents

Old Wold VL:
New World VL:

A

Old Wold VL: L. donovani (aka Kala-azar/ Black Fever)

New World VL: L. chagasi

17
Q

African Trypanosomiasis or Sleeping Sickness

West African:
East African:

A

West African: T. brucei ghambiense (chronic)

East African:T. brucei rhodiesiense (acute)

18
Q

New World or American Trypanosomiasis aka CHAGA`s Disease

A

T. cruzi

19
Q

Direct Inoculation vs Indirect Inoculation

A

Direct means SALIVA (by Sandlfies and Tsetse Flies)

Indirect means DEFECATION (By Kissing Bug)

20
Q

Epimastigote vs Trypomastigote

  1. Undulating membrane
  2. Kinetoplast
A
  1. Undulating membrane
    EPI: Short
    TRYPO: Long
  2. Kinetoplast
    EPI: Anterior to nucleus
    TRYPO: Posterior to nucleus