hemodynamics 2 Flashcards

1
Q

systolic pressure

A

peak aortic pressure

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2
Q

diastolic pressure

A

minimun aortic pressure

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3
Q

blood pressure is expressed as

A

systolic/diastolic

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4
Q

Pulse pressure =

A

Psys – Pdias = 120 – 80 = 40 mmHg

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5
Q

Mean arterial pressure (MAP)=

A

~ Pdias + ⅓(Psys – Pdias) = 80 + ⅓(40) = 93 mmHg

approximate because it depends on heart rate

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6
Q

Pulse pressure, mean pressure, and velocity all _____ through the vasculature.

A

decrease

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7
Q

C (vascular compliance) =

A

C= ΔV / ΔP

C= compliance
V is volume
P is pressure

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8
Q

compliance represents the

A

elastic properties of the vessels or chambers

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9
Q

compliance of arteries

A

absorbs energy and transforms pulsatile flow to continuous flow

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10
Q

____ are more compliant

A

veins are more compliant that arteries

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11
Q

compliance is determined by

A

relative properties of elastin versus smooth muscle and collagen in vessel walls

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12
Q

arteriosclerosis

A

when vessels lose compliance with age

older people have higher systolic pressure and higher pulse pressure than younger people

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13
Q

Law of LaPlace represents the

A

relationship between wall tension and transmural pressure

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14
Q

Law of LaPlace equation

A

T = (ΔP x r) / u

T is wall stress/tension
P is Transmural pressure
r is radius
u is wall thickness

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15
Q

tension in the wall increases as

A

pressure and radius increase

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16
Q

walls of larger vessels are subject to

A

greater tension

17
Q

hypertension increases

A

stress on walls of vessels and chambers

18
Q

an aneurysm increases

A

the radius of the vessel and thus increases the stress on the wall. This is why it can lead to a rupture or dissection

19
Q

Law of LaPlace in the heart chambers

A
  1. decreased wall thickness causes an increased tension

2. increased radius causes an increased tension

20
Q

Cardiovascular transport occurs by

A
  1. bulk transport

2. transcapillary transport

21
Q

Bulk transport

A

refers to movement of a substance through the cardiovascular system from point A to point B

22
Q

Transcapillary transport

A

describes the movement of a substance between capillaries and tissue

23
Q

bulk transport equation

A

x = Q • [x]

x = rate of transport of substance x
Q= flow 
[x]= concentration of substance x
24
Q

how much O2 carried to a muscle in a minute?

A

Delivery in ml O2/min = cardiac output x O2 concentration

25
Q

Fick’s principle is the

A

application of the bulk transport idea to substrate consumption by a capillary bed, a tissue, or the whole body.

simple conversion of mass: amount used is the amount in minus the amount out

26
Q

Fick’s equation

A
Xused = Xi - Xo
Xused = (Q •[x]i) - (Q •[x]o)
Xused= Q ([x]i - [x]o)
27
Q

Q is constant through

A

CV system, so it is the same for initial and final conditions.

28
Q

Fick’s Principle is commonly used to determine

A

cardiac output and myocardial O2 consumption

29
Q

Ficks equation for myocardial oxygen consumption

A

mVo2 = CO ([O2]a - [O2]v)

mVo2 = myocardial oxygen consumption (ml/min)
CO = cardiac output (L/min)
[O2]a = arterial O2 concentration
[O2]v = venous O2 concentration
30
Q

Fick’s equation for cardiac output

A

CO = mVo2/ ([O2]a - [O2]v)