Heme Surface Markers Flashcards
B cell
CD20
CD45
CD79a
Ig kappa
Ig lambda
T cell
CD3 CD7 CD4 CD8 CD45
CD34+
CD38-
blast
CD33 +
myeloid blast (maturing granulocyte)
CD33+
CD34+
CD13+
HLA-DR+
AML with t(15, 17)
CD34+ CD33+ CD17+ CD13+ CD14+ CD11b+
AML with inv (16, 16)
CD10+
CD19+
TdT+
ALL with t(9, 22)
CD10-
CD19+
TdT+
ALL with t(v, 11q23)
CD3+
CD5+
TdT+
T-ALL
CD117+
CD25+
Trypase +
mastocytosis (cKIT mutor FIP1 translocation)
Markers that differentiate between AML and ALL
AML: CD33, 13, HLA-DR, MPO
ALL: CD19, 10, 20, TdT
CDs assc with B cells in germinal centers
CD10
CDs assc with B cells in germinal centers and mantle zones
CD10
CD19
CDs assc with T cells in paracortex
CD3
CD5
CD38+
marker that somatic hypermuatation occurred
BAD prognosis
CD5+
CD23+
light chain restricted
CLL/SLL
CD38+
CD138+
CD19-
CD20-
plasma cell neoplasm
CD19+ CD20+ CD10+ CD22+ CD79a+ Bcl-2+ Surface Ig+
CD5-
Follicular Lymphoma
CD30+
CD15+
CD20-
classical hodgkin
CD20+
CD30-
CD15-`
NLP hodgkin
CD19+
CD20+
CD22+
CD79a+
CD5/-
Surface Ig +/-
CD10 +/-
Diffuse large B cell lymphoma
CD10+ CD19+ CD20+ CD22+ CD79+ surface IgM+
CD5-
CD23-
Burkitt’s Lymphoma