Heme Surface Markers Flashcards
1
Q
B cell
A
CD20
CD45
CD79a
Ig kappa
Ig lambda
2
Q
T cell
A
CD3 CD7 CD4 CD8 CD45
3
Q
CD34+
CD38-
A
blast
4
Q
CD33 +
A
myeloid blast (maturing granulocyte)
5
Q
CD33+
CD34+
CD13+
HLA-DR+
A
AML with t(15, 17)
6
Q
CD34+ CD33+ CD17+ CD13+ CD14+ CD11b+
A
AML with inv (16, 16)
7
Q
CD10+
CD19+
TdT+
A
ALL with t(9, 22)
8
Q
CD10-
CD19+
TdT+
A
ALL with t(v, 11q23)
9
Q
CD3+
CD5+
TdT+
A
T-ALL
10
Q
CD117+
CD25+
Trypase +
A
mastocytosis (cKIT mutor FIP1 translocation)
11
Q
Markers that differentiate between AML and ALL
A
AML: CD33, 13, HLA-DR, MPO
ALL: CD19, 10, 20, TdT
12
Q
CDs assc with B cells in germinal centers
A
CD10
13
Q
CDs assc with B cells in germinal centers and mantle zones
A
CD10
CD19
14
Q
CDs assc with T cells in paracortex
A
CD3
CD5
15
Q
CD38+
A
marker that somatic hypermuatation occurred
BAD prognosis