Heme Onc 3

Question 1

workup of thrombocytopenia

Answer 1

test for HIV and Hep C

then BM bx if neg

Question 2

decreased retic count

Answer 2

leukemia
aplastic anemia
infx
med side effect

Question 3

increased retic count

Answer 3

hemorrhage

hemolysis

Question 4

features of aplastic crisis

Answer 4

severe anemia (transient arrest of erythropoeisis)
decr reticulocytes
NL WBC and plt

Question 5

sxs of acute chest syndrome of sickle cell

Answer 5

fever
chest pain
new infiltrate

Question 6

sxs of splenic sequestration in sickle cell

Answer 6

anemia
incr retic ct
enlarging spleen

Question 7

when to tx prolactinomas

Answer 7

when greater than 10 mm

or symptomatic

Question 8

patient with pernicious anemia should be monitored for

Answer 8

gastric cancer

Question 9

hypercoagulability syndrome associated with lupus

Answer 9

antiphospholipid antibody syndrome

Question 10

main ADR of mycophenolate

Answer 10

bone Marrow suppression

Question 11

major ADR of azathioprine

Answer 11

diarrhea
leukopenia (low WBC)
hepatotoxicity

Question 12

characteristics of CLL and diagnosis

Answer 12

lymphocytosis
lymphadenopathy
hepatosplenomegaly
decr plt and Hb

flow cytometry
smudge cells

Question 13

pre treatment for tumor lysis syndrome

Answer 13

allopurinol

Question 14

positive eosin 5 maleimide binding test

Answer 14

hereditary spherocytosis

Question 15

tx of PNH

Answer 15

iron and folate

eculizumab

Question 16

management of epithelial ovarian carcinoma

Answer 16

ex lap

Question 17

features of waldenstrom macroglobulinemia

Answer 17

hyperviscosity
incr IgM
neuropathy
night sweats
anemia
bruising
vision problems

Question 18

transfusion, then DIC-like reaction (bleeding through transfusion site)

Answer 18

acute hemolytic reaction from ABO incompatibility

Question 19

anaphylactic response to transfusion is from (mechanism)

Answer 19

IgA deficiency

Question 20

indications for thrombolytics in DVT

Answer 20

if large proximal DVT with swelling or limb threatening ischemia
PE with hemodynamic instability

Question 21

CA 19-9 indications

Answer 21

post op for pancreatic cancer to monitor response to chemotherapy

Question 22

labs of sideroblastic anemia

Answer 22

incr iron
incr ferritin
NL TIBC