Heme Onc 2 Flashcards

1
Q

Hb 7-8, indications for blood transfusion

A

cardiac surgery
heart failure
oncology patient in tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hb 8-10 indications for blood transfusion

A

symptomatic anemia
ongoing bleeding
ACS
noncardiac surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

both B12 and folate convert…

A

homocysteine to methionine

so deficiencies lead to elevated homocysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

TTP peripheral blood smears show

A

schistocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hereditary spherocytosis causes what type of gallstones

A

pigment gallstones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hereditary spherocytosis requires supplementation of

A

folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

does your body have lower stores of B12 or folate?

A

folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pernicious anemia causes what type of vitamin deficiency

A

B12 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

myelodysplastic syndrome labs

A

pancytopenia

macrocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

positive fibrin degradation products signify

A

DIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

myelocytes and metamyelocytes… differential and how to differentiate the two

A

leukemoid reaction vs CML
leukemoid reaction: more mature, so more metamyelocytes than myelocytes, high alk phos
CM: less mature, so less metamyelocytes than myelocytes, low alk phos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

vegetarian anemia

A

B12, after about 3-4 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

poor diet anemia

A

folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

fatigue, SOB, URI treated with amoxicillin, splenomegaly, anemia, reticulocytosis

  • dx
  • tx
A

autoimmune hemolytic anemia

glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

CHOP therapy is used to treat

A

non Hodgkins lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

B12 deficiency can be caused by

A

pernicious anemia
short bowel syndrome
vegan

17
Q

MCV / RBC (Mentzner index) less than 13

A

thalassemia

18
Q

MCV / RBC (Mentzner index) greater than 13

A

iron deficiency anemia (b/c decr RBC)

19
Q

von willebrand disease labs

A

incr bleeding time and PTT

normal PT

20
Q

factor 8 deficiency labs

A

prolongs PTT

21
Q

qualities of gloms tumor

A

tender
sensitivity to touch
intermitent pain

22
Q

dx testicular tumor on US. next step

A

radical orchiectomy

23
Q

traztuzumab cuases ___

and next step

A

cardiotoxicity

echo

24
Q

peripheral smear of ITP

A

megakaryocytes

25
Q

management of adult with ITP

A

if platelets less than 30,000 or bleeding, IVIG or glucocorticoids
if not, obs

26
Q

sxs of Bernard Soulier

A

bleeding out of proportion to the mild thrombocytopenia

27
Q

labs of DIC

A

low platelets

incr PT and PTT

28
Q

labs of vWD

A

incr bleeding time and PTT

29
Q

labs of hemophilia

A

incr PTT

30
Q

management of heparin induced thrombocytopenia

A

stop heparin

dx with serotonin release assay OR start argatroban or fondaparinux