Hematopoietic Malignancies 2

Question 1

Diagnosis for Chronic Lymphocytic Leukemia

Answer 1

Flow cytometry can confirm leukemia

Question 2

Leukemia is based on which main cell type

Answer 2

Lymphoid

Question 3

4 criteria to meet the diagnosis of Multiple Myeloma (need 2 out of 4)

Answer 3

1) Plasma cell infiltrate in bone marrow or other organ
2) Monoclonal gammopathy in serum
3) Monoclonal gammopathy in urine (Bence-Jones Proteinuria)
4) Osteolytic bone lesions

Question 4

Diagnosis for Acute Lymphoblastic Leukemia

Answer 4

CBC -> thrombocytopenia is very common

Question 5

Treatment for Histiocytic Sarcoma

Answer 5

Chemotherapy (CCNU/Doxorubicin)

Question 6

What treatment is an oral lifelong administration for Multiple Myeloma

Answer 6

Melphalan

Question 7

MBD for Polycythemia Vera

Answer 7

Erythrocytosis (HCT: 65-80%)

Question 8

Treatment for Acute Lymphoblastic Leukemia

Answer 8

CHOP based chemotherapy

~50% respond, MST= 5 months

Question 9

Treatment for Chronic Lymphocytic Leukemia

Answer 9

Chlorambucil (oral) and prednisone

Question 10

Name of disease that is a benign , dermal mass , “strawberry” lesion

Answer 10

Histiocytoma