Chemotherapy 2 Flashcards
Which chemotherapy drug stimualtes the CRTZ (vomiting)?
Cisplatin
Which systemic therapy is used for carcinomas such as Transitional Cell Carcinomas (TCC)?
NSAIDs
Which of the following would be the most important in the safe administration of Doxorubicin?
A) Quiet, low traffic environment
B) Animals sedated for the procedure
C) Well trained technicians
D) Spill kit on hand
A) Quiet, low traffic environment
5 Families of Drugs
1) Alkylating agents
2) Antimetabolites
3) Antitumor antibiotics/antrhracyclines
4) Spindle toxins: vinca alkaloids, taxanes
5) Miscellaneous agents
Which chemotherapy drug has hepatotoxicity?
CCNU (Lomustine)
Which chemotherapy drug is cardiotoxic (irreversible) for dogs and nephrotoxic for cats?
Doxorubicin
Name of the drug that does suppresion of T lymphocytes leading to BV inhibition
Cyclophosphamide
Name of the drug that is a tyrosine kinase inhibitor that has c-kit and labelled to treat mast cell tumors
Palladia (Toceranib)
Which chemotherapy drug has a fatal idiosyncratic pulmonary edema in cats?
Cisplatin
Which phase does the spindle toxins act on?
M phase
Cyclophosphamide (Cytoxan) and CCNU (Lomustine) are classified under what type of chemotherapy drugs
Alkyating Agents
What phase does antitumor antibiotics/anthracyclines act on?
S phase
Preventive measures should be used to minimize exposure of chemotherapy agents to veterinary staff. The greatest risk of systemic absorption of chemotherapy agents by staff is via which of the following routes:
A) Absorption through the skin
B) Accidental injection
C) Inhalation of an aerosol
D) Accidental ingestion
C) Inhalation of an aerosol
Which chemotherapy drug has a common GI toxicity due to ileus?
Vincristine
Which chemotherapy drug has a toxicity of sterile hemorrhagic cystitis?
Cyclophosphamide (Cytoxan)
