Canine and Feline Skin Tumors

Question 1

Prognostic factors for Osteosarcoma:

• Mandible -> _____ prognosis
• Scapula -> _____ prognosis

Answer 1

• Mandible -> better prognosis
• Scapula -> worse prognosis

Question 2

1 bone tumor for dogs and cats

Answer 2

Osteosarcoma

Question 3

3 forms of Feline Mast Cell Tumors

Answer 3

1) Cutaneous (histiocytic and mastocytic)
2) Splenic
3) Intestinal (rare)

Question 4

2 highest drugs reported most anti-MCT activity

Answer 4

1) Toceranib (Palladia) -> 60% response
2) Masitinib (Kinavet) -> 60% response (35% alive at 2 years)

Question 5

Histologic grading is subjective to degree of: (6 things)

Answer 5

1) Location/degree of invasion
2) Architecture and stromal reaction
3) Nuclear morphology
4) Cell morphology
5) Edema and necrosis
6) Mitotic figures

Question 6

4 Classic Signs of inflammation

Answer 6

1) Tumor -> swelling
2) Calor -> heart
3) Rubor -> redness
4) Dolor -> pain

Question 7

What is the most common skin tumor (11-27%) in dogs?

Answer 7

Canine Mast Cell Tumors

Question 8

Clinical Signs of Feline Mastocytic and Compact

Answer 8

Head and neck most common

Question 9

Which Feline MCT is more common than in dogs?

Answer 9

Feline Splenic MCT

Question 10

Which 2 MCT cases have an excellent prognosis?

Answer 10

1) Completely excised grade 1
2) Completely excised grade 2

Question 11

Name of drug that is tyrosine kinase inhibitor, approved for dogs, labelled to treat mast cell tumors

Answer 11

Palladia (Toceranib)

Question 12

Treatment of choice for Intestinal MCT

Answer 12

Cut it out

Question 13

Treatment for Osteosarcoma

Answer 13

Surgery

• amputation
• limb spare

Question 14

3 criteria for Task Force Recommendations

Answer 14

1) More than 2 cm
2) Nodule is present 3 months after vaccine
3) Increasing in size at more than 4 weeks after vaccine

Question 15

Which form of feline MCT is most commonly seen?

Answer 15

Mastocytic form

Question 16

Osteosarcoma tumor location

Answer 16

75% appendicular skeleton

towards the knee, away from the elbow

Question 17

Treatment for Cutaneous Mast Cell Tumor

Answer 17

Surgery

Wide surgical excision

2-3 cm margins, 1 fasical plane deep

Question 18

Breed predisposition with high grade Mast Cell Tumor

Answer 18

Chinese Shar Pei

Question 19

3 common sites for Soft Tissue Sarcomas to metastasize

Answer 19

1) Lung
2) Liver
3) Lymph nodes

Question 20

Cytologic appearance of Cutaneous Mast Cell tumor

Answer 20

Large round to oval mast cells often with purple granules

Question 21

Diagnostic required for Cutaneous Mast Cell Tumor diagnosis

Answer 21

FNA

Question 22

Feline MCT granules often seen more eosinophilic than Canine MCT

True or False?

Answer 22

True

Question 23

2 Staging tests for Cutaneous Mass Cell Tumor

Answer 23

1) ***Lymph node aspirate***
2) Bone marrow aspirate