hematopoiesis 1 Flashcards

1
Q

true/false: blood is a connective tissue

A

true

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2
Q

what is a normal volume of blood for a person?

A

5L/person

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3
Q

what molecule does oxygen bind to?

A

hemeglobin

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4
Q

what are the components of blood?

A

erythrocytes (RBC), Leukocytes (WBC), thrombocytes (Platelets), Plasma

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5
Q

what is hematopoiesis?

A

the formation of blood

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6
Q

about how much blood gets replaced daily by the human body?

A

about 1 percent

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7
Q

what are the 2 branches of the hematopoietic stem cell?

A

lymphoid and myeloid progenitor

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8
Q

describe hemostasis

A

the stopping of blood loss
think of homeostasis but for blood

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9
Q

what are the stages of hemostasis?

A

vessel spasm, platelets, clotting, clotting retraction, clotting resolution

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10
Q

what are some diseases of the WBC?

A

leukemia, lymphoma (H&NH), neutropenia

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11
Q

what are some diseases of RBC?

A

anemia (iron deficient, pernicious, hemolytic, etc)

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12
Q

what is going to be the main purpose of the WBC

A

to fight off infections

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13
Q

true/false: the normal WBC is between 5k-10k

A

true

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14
Q

what is leukopenia?

A

decreased WBC

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15
Q

what is leukocytosis?

A

increased WBC

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16
Q

what happens to the number of neutrophils during an infection?

A

they increase

17
Q

what does the suffix -penia indicate?

A

decrease/lowering

18
Q

describe neutropenia

A

the lowering of neutrophils, this also lowers the body’s ability to fight infection

19
Q

what are some clinical manifestations of neutropenia ?

A

fever, chills, infections of the lungs & orafaces

20
Q

how do we diagnose and treat neutropenia?

A

we do a bone marrow biopsy, treat with antibiotics & hemolytic growth factors

21
Q

what are some things that can cause neutropenia?

A

drug usage, cancer treatment, certain cancers

22
Q

what is the disease that causes Mononucleosis?

A

Epstein Bar Virus

23
Q

what are some clinical manifestations?

A

anorexia, chills, fever, sore throat, etc

24
Q

what happens to the individual when the symptoms of mono subside?

A

the b cells are left behind and the individual has asymptomatic mono for life, also there is immunity from contracting the disease

25
Q

what is a lymphoma?

A

a cancer that attacks the lymphatic system

26
Q

what are some risk factors for having lymphoma?

A

exposure to pesticides, autoimmune disorders, HIV&Mono, etc

27
Q

what are some clinical manifestations of a lymphoma?

A

enlarged lymph nodes, wight loss, fever, fatigue

28
Q

which is the less common lymphoma?

A

Hodgkin lymphoma

29
Q

describe the process of hodgkin lymphoma

A

large b cells originate in the upper body, they then spread to the other parts of the lymphatic system

30
Q

is the prognosis for hodgkin lymphoma good or not good?

A

good. there is a solid treatment for this

31
Q

how do we diagnose Hodgkin lymphoma?

A

CBC, Lynmph node biopsy,

32
Q

how do we treat hodgkin lymphoma?

A

we do radiation and chemo

33
Q

understand the stages of hodgkin lymphoma

A

the b cells start in the lymph nodes and can travel greatly throughout the body increasing in severity from stages 1-4

34
Q
A