hematopoiesis 1 Flashcards

1
Q

true/false: blood is a connective tissue

A

true

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2
Q

what is a normal volume of blood for a person?

A

5L/person

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3
Q

what molecule does oxygen bind to?

A

hemeglobin

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4
Q

what are the components of blood?

A

erythrocytes (RBC), Leukocytes (WBC), thrombocytes (Platelets), Plasma

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5
Q

what is hematopoiesis?

A

the formation of blood

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6
Q

about how much blood gets replaced daily by the human body?

A

about 1 percent

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7
Q

what are the 2 branches of the hematopoietic stem cell?

A

lymphoid and myeloid progenitor

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8
Q

describe hemostasis

A

the stopping of blood loss
think of homeostasis but for blood

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9
Q

what are the stages of hemostasis?

A

vessel spasm, platelets, clotting, clotting retraction, clotting resolution

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10
Q

what are some diseases of the WBC?

A

leukemia, lymphoma (H&NH), neutropenia

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11
Q

what are some diseases of RBC?

A

anemia (iron deficient, pernicious, hemolytic, etc)

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12
Q

what is going to be the main purpose of the WBC

A

to fight off infections

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13
Q

true/false: the normal WBC is between 5k-10k

A

true

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14
Q

what is leukopenia?

A

decreased WBC

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15
Q

what is leukocytosis?

A

increased WBC

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16
Q

what happens to the number of neutrophils during an infection?

A

they increase

17
Q

what does the suffix -penia indicate?

A

decrease/lowering

18
Q

describe neutropenia

A

the lowering of neutrophils, this also lowers the body’s ability to fight infection

19
Q

what are some clinical manifestations of neutropenia ?

A

fever, chills, infections of the lungs & orafaces

20
Q

how do we diagnose and treat neutropenia?

A

we do a bone marrow biopsy, treat with antibiotics & hemolytic growth factors

21
Q

what are some things that can cause neutropenia?

A

drug usage, cancer treatment, certain cancers

22
Q

what is the disease that causes Mononucleosis?

A

Epstein Bar Virus

23
Q

what are some clinical manifestations?

A

anorexia, chills, fever, sore throat, etc

24
Q

what happens to the individual when the symptoms of mono subside?

A

the b cells are left behind and the individual has asymptomatic mono for life, also there is immunity from contracting the disease

25
what is a lymphoma?
a cancer that attacks the lymphatic system
26
what are some risk factors for having lymphoma?
exposure to pesticides, autoimmune disorders, HIV&Mono, etc
27
what are some clinical manifestations of a lymphoma?
enlarged lymph nodes, wight loss, fever, fatigue
28
which is the less common lymphoma?
Hodgkin lymphoma
29
describe the process of hodgkin lymphoma
large b cells originate in the upper body, they then spread to the other parts of the lymphatic system
30
is the prognosis for hodgkin lymphoma good or not good?
good. there is a solid treatment for this
31
how do we diagnose Hodgkin lymphoma?
CBC, Lynmph node biopsy,
32
how do we treat hodgkin lymphoma?
we do radiation and chemo
33
understand the stages of hodgkin lymphoma
the b cells start in the lymph nodes and can travel greatly throughout the body increasing in severity from stages 1-4
34