Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHARM 343 > Hematology, Liver, GI Lab > Flashcards

Hematology, Liver, GI Lab Flashcards

1
Q

Agranular WBC

A

Monocytes

Lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Liver Function Tests

A

Albumin

Clotting Factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anemia Lab Tests

A

Ferritin

Vit B12

Folic Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Gamma-Glutamyl Transpeptidase
- What
- Where
- Meaning

A

Biliary excretory enzyme

Kidney, Spleen, Heart, Brain
- NOT bone or placenta

Concurrent rise with ALP indicate hepatobiliary disease

Rise in GGT = Alcohol abuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

C-Reactive Protein

A

Rapid test for inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

GI Lab Values

A

Digestive Enzymes
- Amylase
- Lipase

Indication of:
- Poor exocrine function of pancreas
- Blockage of ducts / gallbladder problem
- Inflammation / blockage of salivary gland
- Chronic kidney disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Neutrophils

A

Segmented
- Phagocytosis
- Release proteins to destroy foreign stuff

Band
- Small amount of Immature cells. Increases in proportion during infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Lactic Acid Dehydrogenase

A

Metabolic enzyme present in almost every tissue
- Elevated levels indicate cell damage

(Liver disease, lung disease, lymphoma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Liver Injury Tests

A

Aminotransferases (AST and ALT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Low Albumin

A

Chronic Liver Disease

Peripheral Edema and Ascites (Low Osmotic Pressure)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Mean Corpuscular Hemoglobin Concentration

A

Average concentration of hemoglobin per volume of RBC
- Hypochromic, Normochromic, Hyperchromic

MCHC = Hgb / Hct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Eosinophils

A

Allergic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Lymphocyte

A

B-Cell
- Transform into plasma cells to produce antibodies

T-Cell
- Cell mediated immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Reticulocyte Count

A

Amount of immature RBC

Reflects bone marrow production of RBC
- Good for diagnosis of anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Cholestasis

A

Accumulation of substances that would normally be excreted by the liver into bile

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Aminotransferase

A

Assist with protein metabolism and metabolic processes in general

ALT - Specific for liver injury
AST - Other parts of the body (muscle injury)

17
Q

Red Blood Cell Indices

A

Information on Size and Hemoglobin content
- Calculated from RBC, Hemoglobin, Hematocrit

18
Q

Ferritin Lab Value

A

Stored Iron Complex
- How much iron stored in the body

Iron Deficiency = Microcytic Hypochromic Anemia

19
Q

Assessing ALP and GGT

A

High ALP + High GGT
- Hepatic Source

High ALP + Low GGT
- Non-Hepatic Source

20
Q

Alkaline Phosphatase
- What
- Where
- Meaning

A

Transporter that moves metabolites past cell membrane

Placenta, Bone, GI cells

Cholestasis enhances ALP as there is a blockage

21
Q

Cholestasis Identification Tests

A

Alkaline Phosphatase

Gamma-Glutamyl Transpeptidase

22
Q

Vit B12 Lab Value

A

Vit B12 Deficiency = Low Stomach Acid

Macrocytic Normochromic Anemia

23
Q

Complete Blood Count

A

Number of each type of Blood Cell
- Platelet
- RBC
- WBC

24
Q

Red Cell Distribution Width

A

Cell Size Distribution

25
Q

Complete Count With Differential

A

Number of each type of Blood Cell
- Platelet
- RBC
- Different types of WBC

26
Q

Symptoms of Cholestasis

A
  • Jaundice
  • Pruritus
  • Xanthomas
  • Malabsorption of Fat Soluble Vitamins
  • Anorexia
27
Q

Monocytes

A

Mature into macrophages

Can also develop into foam cell if clearing lipids

28
Q

Mean Corpuscular Hemoglobin

A

Average weight of hemoglobin in RBC

MCH = Hgb / RBC Count

29
Q

Bilirubin

A

Produced when Liver breaks down RBC

High Bilirubin indicates jaundice

30
Q

When do we need dosage adjustments

A

Compromised liver function + drug with high first pass metabolism

Compromised liver function + drug that requires activation by liver

31
Q

Low Clotting Factors

A

Excessive bleeding

32
Q

Folic Acid Lab Value

A

Involved in maturation of RBC

Low Vit B12 is followed by low Folic Acid

33
Q

Basophils

A

Develop into mast cells

Contains:
- Heparin (Anticlotting)
- Histamines (Promote allergic response)
- Proteolytic Enzymes

34
Q

Non-Specific Markers Tests

A

Bilirubin

Lactic Acid Dehydrogenase

35
Q

Granular WBC

A

Neutrophils

Basophils

Eosinophils

36
Q

What medication therapies require looking at Liver Lab Values

A

HIV medications

Tuberculosis medications

Rheumatoid Arthritis medications

Statins

Isotretinoin

Or if patient is experiencing jaundice

37
Q

Erythrocyte Sedimentation Rate

A

Rate blood falls in a tube (Sedimentation Rate)
- Should very slow

Inflamed blood will fall faster (Higher sedimentation rate)

38
Q

Mean Corpuscular Volume

A

Average Size of RBC
- Normocytic, Microcytic, Macrocytic

MCV = Hct / RBC Count

PHARM 343 (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions