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T's Haematology Y5 > Hematology in systemic disease > Flashcards

Hematology in systemic disease Flashcards

1
Q

what are the inherited causes of haemolytic anaemias

A

memb def - heri spherocytosis
cytoplasm/enz - G66PD def
Hb - SCD/thall

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2
Q

two main types of acquired haemolytic anaemias and differences in presentation

A

immune med -> DAT+, agglutination, spherocytosis

Non-immune med ->DAT-, schistocytes, thrombocytopenia

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3
Q

types of immune med acquired haemolytic anaemia

A

Warm - IgG med, extravasc

Cold - IgM med, intravasc

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4
Q

causes of non-immune med acquired haemolytic anaemia

A

inf (esp malaria)
paroxysmal noctural haemoglobinuria
MAHA (due to adenocarcinoma/HUS/TTP)

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5
Q

what can be said about myeloblast levels in bone marrow

A

> 5% myeloblasts = abnormal

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T's Haematology Y5 (16 decks)

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