Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Clinical I > Hematology & Erythropoiesis > Flashcards

Hematology & Erythropoiesis Flashcards

1
Q

What are the main functions of blood?

A

Transport, maintain body temperature and pH, and protection in the form of clot formation and prevention of infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What kind of tissue is blood classified as?

A

Connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the normal percent bodyweight of most animals’ blood volume?

A

About 7%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The normal blood volume of most animals is about _____mL/kg

A

70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The normal blood volume of most cats is about _____mL/kg

A

40

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Blood is made of about 40% _________ and 60% ________

A

formed elements; plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

About what percentage of plasma is water?

A

91-92%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

About what percentage of plasma is protein?

A

7-8%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the largest protein in blood and what is its function?

A

Fibrinogen; it is made in the liver and its main purpose is to clot blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What cells are globulins made by?

A

Plasma cells (B lymphocytes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the smallest protein in blood and what is its function?

A

Albumin; it is made in the liver and it maintains oncotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Approximately 1-2% of blood is made of other solutes (not water or protein), what are some of those other solutes?

A

Electrolytes, non protein nitrogenous waste products, nutrients, and regulatory substances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the difference between serum and plasma?

A

Serum is plasma without the clotting factors (fibrinogen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

_______ are located exclusively in the vascular system, whereas _______ are located mainly outside the vascular system

A

Erythrocytes; leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the function of thrombocytes?

A

Hemostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Acidic stains bind to ______ compounds and stain (color)

A

Basic; red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Basic stains stain ______ structures and stain (color)

A

Acidic; blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

All bone marrow is hematopoietic in early life, but upon maturing, the demand for red blood cells decreases, and red bone marrow moves mainly from the _______ skeleton to the _______ skeleton

A

Appendicular; axial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

This is the type of cell that erythrocytes, megakaryocytes, granulocytes, and lymphocytes all derive from

A

Pluripotential stem cell

20
Q

From what organ is erythropoietin secreted?

A

Kidneys

21
Q

What stimulates erythropoietin secretion?

A

Renal hypoxia

22
Q

Approximately how many days to RBCs spend in the red bone marrow before entering circulation?

A

5-6 days

23
Q

While the RBCs are maturing in the bone marrow, why does their cytoplasm change color from blue to red?

A

Because as RBCs mature, they begin to lose their RNA. RNA, being acidic, stains blue. As it begins to leave the maturing RBCs, the cytoplasm becomes less acidic and more basic, staining red

24
Q

What is the average life span of a red blood cell?

A

90-120 days

25
Q

What is the first morphologically identifiable erythroid precursor?

A

Rubriblast

26
Q

What color to rubriblasts stain?

A

Blue

27
Q

Is the chromatin pattern of a rubriblast loose or tight?

A

Loose

28
Q

What is similar to a rubriblast, but slightly smaller, has a very blue cytoplasm, a round nucleus, and no identifiable nucleolus?

A

Prorubricyte

29
Q

Rubricytes generally have a ____ located, ____ nucleus

A

Centrally; round

30
Q

This cell is the last stage of developing erythrocyte that is able to divide mytotically

A

Rubricyte

31
Q

Metarubricytes have cytoplasm that is beginning to become ___________

A

Polychromatophilic; meaning stainable with more than one type of stain and especially with both acid and basic dyes

32
Q

What type of cell is known as a “reticulocyte” when it is stained with New Methylene Blue?

A

Polychromatophilic erythrocyte

33
Q

What is the only species that has punctate reticulocytes?

A

Cat

34
Q

What species never circulates reticulocytes?

A

Horses

35
Q

What type of animal circulates reticulocytes if they’re anemic?

A

Ruminants

36
Q

What species has the smallest erythrocytes?

A

Goats

37
Q

What species’ RBCs have the most distinct central pallor?

A

Dogs

38
Q

What is the diameter of a normal erythrocyte?

A

4-8 micrometers

39
Q

What does it mean that it’s normal for RBC’s to have a slight anisocytosis?

A

That the cells have a slight variation in size

40
Q

What does rouleax formation indicate?

A

High protein

41
Q

What species shows the greatest degree of rouleaux?

A

Horses

42
Q

In what species is rouleax formation not found?

A

Bovine

43
Q

What species normally has spindle form and fusiform RBCs?

A

Angora goats

44
Q

What types of animals normally have elliptical, nucleated RBCs?

A

Birds, amphibians, fish, and reptiles

45
Q

What genus of animals normally have elliptical, anucleated RBCs?

A

Camelidae

46
Q

What type of animals normally have sickle shaped RBCs?

A

Deer

47
Q

What is the main function of an erythrocyte?

A

To carry hemoglobin for the transport of oxygen and the removal of carbon dioxide

Clinical I (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions