Hematology/BW Flashcards
what is the normal MCV?
80-100
what is the most common microcytic anemia
iron deficiency anemia
would anemia of chronic disease most likely be macrocytic, normocytic, or microcytic
normocytic
what two main causes should you be thinking of in a macrocytic anemia
malnutricion and sever blood loss
does an increase in reticulocytes indicate a decrease or an increase in RBC production
An increase, reticulocytes are newly released “baby” RBCs
Auer Rods are most commonly associated with what disease
Acute Myeloid leukemia
what molecule binds iron in the blood stream
transferrin
what does koilonychia refer to?
spoon shapped nails. this may be found in microcytic anemia
will the serum ferritin be high or low in a patient with iron deficiency anemia
it will almost always be low
a low retic count and a normal serum ferritin should make you think of what diagnosis
anemia of chronc disease
under normal conditions at what hemoglobin level would you begin to consider a transfusion
8
Asplenism secondary to sickle cell disease increases a patients risk for what type of infections
Capsulated organisms like Strep Pneumo and H. Flu
An african american teenager presents with avascular necrosis of the his right femoral head. what is the most likely diagnosis
Sickle cell disease
How do you treate sickle cell crisis
Fluids, oxygen, pain medication, transfusion may be nevessary
Will unconjugated bilirubin be high or low in a patient with sickle cell disease
HIgh
which anemia should you think of if you see the term Howell-Jolly Bodies
Sickle cell due to functional asplenia but it may also show up in a folic acid deficiency
G6PD deficiency follows what pattern of inheritance
x-linked
list the 3 diagnosis you should be thinking of if a question includes Heinz bodies
G6PD deficiency anemia, chronic liver disease, alpha thalassemia
what is pica
eating non food items including ice, paper, dirt, hair
Are target cells seen in mild or sever iron deficiency anemia
Severe, they are also seen in alpha thalassemia, chornic liver disease and asplenia
iron deficiency anemia will have a serum iron lower than what value
30
woud a B12 deficiency anemia most likely be microcytic, normocytic or macrocytic
macrocytic
you should be thinking alpha thalassemia if the question stem includes which four geographic areas
Southeast Asia, MIddle East, Africa
A patient of mediterranean descent is a clue for which type of anemia
Beta thatassemia
In a folic acid deficiency anemia the folic acid level is typically below what level
<150
What hematological disorder should you think of if the questions talks about the patient eating ice or dirt
Iron deficiency anemia
Inability to absorb vitamin B12 due to lack of intrinsic factor is what disease
Pernicious Anemia
Stocking glove paresthesias should make you think of what two diagnosis
B12 deficiency neuorpathy and diabetic neuropathy
will the rbs’s be large, small, or normal size in a B12 deficient anemia
Macrocytes
Will the retic count be elevated, decreased, or normal in a B12 deficient anemia
Retic count will be low. low building blocks means low production
what is Schillings test used for?
test for the cause of B12 deficiency
Strict vegans are at risk for what type of anemia
B12 deficiency Anemia
Is sickle cell microcytic, macrocytic or normocytic
microcytic
will a hemolytic anemia generally have an elevated or a decreased retic count?
elevated
list for disease states in which you may find basophilic stippling
lead poisoning, Beta or Alpha thalassemia, sideroblastic anemia, arenic poisoning
if a question presents a pregnant woman with anemia what is the most likely diagnosis
Iron Deficiency
The Term Philadelphia Chromosome you should make you think of what diagnosis
Chronic Myeloid Leukemia
