Hematology

Question 1

What are erythroblasts?

Answer 1

Baby red blood cells

Question 2

Do mature red blood cells have DNA?

Answer 2

No they have no DNA or RNA which means they can’t synthesize proteins for cell functions

Question 3

What is the lifespan of a red blood cell?

Answer 3

100 to 120 days

Question 4

How many days does it take for a stem cell to differentiate into a mature red blood cell?

Answer 4

Seven days

Question 5

What are the four components of blood cells?

Answer 5

There are leukocytes, lymphocytes, erythrocytes, and platelets.

Question 6

Where is blood composed of in the fetus?

Answer 6

The liver

Question 7

where is blood composed of in children and adults? 4 places

Answer 7

Ribs, sternum, vertebrae, Ilium

Question 8

What is the shape of a red blood cell?

Answer 8

Biconcave

Question 9

What is hemoglobin?

Answer 9

Iron containing protein

Question 10

What organ can detect when there is an increase need for oxygen?

Answer 10

The kidneys Can detect the need

Question 11

What do kidneys secrete when there’s a need for additional red blood cells?

Answer 11

Erythropoietin

Question 12

Iron, folate, vitamin B12 and intrinsic factors help support what?

Answer 12

Erythropoiesis

Question 13

Where is iron absorbed from?

Answer 13

The G.I. tract

Question 14

Iron stored in the liver is called what?

Answer 14

Ferritin

Question 15

Iron is transported as what to the liver?

Answer 15

Transferrin

Question 16

From the liver ferritin is transported as what to the bone for incorporation in hemoglobin?

Answer 16

Transferrin

Question 17

Two alpha chains in the fetus composes what type of hemoglobin

Answer 17

Hemoglobin F

Question 18

How many weeks out after birth, does the alpha chains and the beta chains pair to result adult hemoglobin A.

Answer 18

18 weeks-24 weeks after birth

Question 19

What is the four unit structure hemoglobin called?

Answer 19

Tetramer

Question 20

What is a normal RBC count?

Answer 20

4.2–6.2

Question 21

What is the hematocrit range?

Answer 21

37-52%

Females: 37-47%

Males: 42-52%

Question 22

What is the normal hemoglobin range?

Answer 22

12 to 18 (think difference of 4 from the highest and lowest)

Females: 12–16

Males: 14–18

Question 23

1g of hemoglobin is about how much percentage of hematocrit?

Answer 23

3% of hematocrit

Question 24

What type of genetic disorder is pernicious anemia?

Answer 24

Autosomal recessive genetic disorder

Question 25

What is pernicious anemia?

Answer 25

Deficiency of intrinsic factor in resulting in the inability to absorb vitamin b12

Question 26

What is vitamin b12 deficiency anemia?

Answer 26

Due to dietary deficiency or impaired intestinal absorption, rather than lack of intrinsic factor

Question 27

What disease or conditions are associated with vitamin B 12 deficiency?

Answer 27

Crohn’s disease 
Celiac disease 
Vegetarianism 
Excessive alcohol consumption 
Acid reducing medication

Question 28

What does the Schilling test confirm?

Answer 28

Confirms low vitamin b12 level is due to intrinsic factor deficiency