Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

EOR: Family Medicine > Hematology > Flashcards

Hematology Flashcards

1
Q

Normal or ↓ MCV
↓ TIBC
↑ Ferritin (high iron stores)
↓ serum erythropoietin

A

anemia of chronic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

↓ MCV (microcytic)
↓ MCH (hypochromic)
↑ TIBC
↓ Ferritin (best test, low iron stores)

Target cells, pica, and nail spooning

A

IDA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Tx of IDA…

A

Ferrous sulfate 325mg TID + CBC.q 3 mo

PRBCs if Hg < 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

+ Heinz Bodies and Bite Cells on smear

A

G6PD Deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

(+ Direct Coombs Test)

A

Autoimmune hemolytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

(+) osmotic fragility test, spherocytes

A

hereditary spherocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The below lab profile indicates what type of anemia?

↑ Retic
↑ LDH
↓ Haptoglobin
↑ Bilirubin (indirect)

A

hemolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Very ↑ Retic count

howell-jolly bodies

target cells

A

sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

profoundly decreased MCV

normal TIBC/Ferritin

Elevated iron

A

thalassemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tx of beta thalassemia

A

transfusion

desferoxamine (chelation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hg electrophoresis shows HbA2 and HbF…

A

beta thalassemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Hg electrophoresis shows HbA2

A

Beta thalassemia trait

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Chinese/SE Asians

Hg electrophoresis shows HgH, HgBart’s

A

Alpha thalassemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Smooth beefy, sore tongue. Neurologic symptoms

A

B12 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Diagnostic for pernicious anemia…

A

schilling test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

recurrent history of nosebleeds and heavy menses, recent nosebleeds

FHx of similar sxs

Incrased PTT, bleeding time

NORMAL PT

A

von willebrand disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

This disease has missing factor that prevents platelets to adhere to the vessel wall. Therefore, bleeding doesn’t stop as quickly as it should

A

vWD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How can you differentiate vWD and hemophilia?

A

lack of hemarthrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tx of vWD

A

DDAVP (desmopressin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Missing clotting factor VIII

A

hemophilia A (aight)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Missing clotting factor IX… christmas disease…

A

Hemophilia B

22
Q

Genetic inheretance of hemophilia

A

X linked (will affect males)

23
Q

Hemarthrosis

Increased PTT
Normal PT and Platelets

A

hemophilia

24
Q

Which leukemia?

Pediatric patient

LAD

Bone Pain

Bleeding

Fever

A

ALL

25
Q

20% blasts in bone marrow can indicate which leukemia?

A

ALL

26
Q

Which leukemia?

Middle age patient (peak age 50)

Sometime asymptomatic

+/- fatigue, LAD, splenomegaly

A

CLL

27
Q

Dx of CLL

A

Smudge cells and mature lymphocytes on peripheral smere

28
Q

Tx of CLL

A

observation… if lymphocytes > 100,000 start chemo

29
Q

Which leukemia?

Adult patient

Anemia, thrombocytopenia, neutropenia.

Splenomegaly, gingival hyperplasia and Leukostasis (WBC > 100k)

A

AML

30
Q

Which leukemia?

Aur rods and 20% blasts in bone marrow

A

AML

31
Q

Which leukemia?

Strikingly increased WBCs (> 100k)

Hyperuricemia

Adult patient

A

CML

32
Q

Dx of CML can be done via…

A

philadelphia chromosome

33
Q

AML can be treated with…

A

bone marrow transplant

34
Q

Which lymphoma has bimodal peaks in 20s and 50s?

A

hodgkin’s

35
Q

non-hodgkins is common in what age group?

A

> 50 yo

36
Q

Reed sternberg cells indicate…

A

hodgkin’s

37
Q

Which lymphoma?

Painless LAD with contiguous spread to local lymph nodes

A

hodgkin’s

38
Q

Which lymphoma?

extranodal spread to GI and skin lymph nodes

A

non-hodgkin’s

39
Q

Which lymphoma?

B sxs present

a/w EBV

A

hodgkin’s

40
Q

Mediastinal adenopathy on CXR indicates which lymphoma?

A

hodgkin’s

41
Q

Which lymphoma?

SOB
intussusception
bowel obstruction
abdominal mass

A

non-hodgkin

42
Q

biologic available for non-hodkin lymphoma

A

rituximab

43
Q

Patient presents with:

pruritis after hot baths

burning pain

rubor of hands/feet (redness)

A

polycythemia vera

44
Q

4 Hs of polycythemia vera…

A

hypervolemia (increased RBCs)

Hisaminemia

Hyperviscosity (Increased Hct)

Hyperuricemia

45
Q

Tx of polycythemia vera…

A

repeated phlebotomy

46
Q

Tx for DIC…

A

cryoprecipitate, FFP, heparin

47
Q

Bleeding and thrombosis occuring at the dsame time…

Decreased platelets

increased bleeding time, PT, PTT, D-Dimer

A

DIC

48
Q

Autoimmune reaction to platelets usually after a viral illness

Insidious onset, chronic

A

idiopathic throbocytopenic purpura (ITP)

49
Q

Associated with HIV, HCV, SLE, CLL

CBC normal except low platelets. (+ Direct Coombs Test)

A

idiopathic throbocytopenic purpura (ITP)

50
Q

↓ Platelets + anemia + schistocytes (RBC fragments) on smear and NEG Coombs

After administration of quinidine, cyclosporine or pregnancy

A

TTP

51
Q

Purpura and “FAT RN”-

Fever
Anemia
Thrombocytopenia
Renal failure
Neurological symptoms
A

TTP

52
Q

Post-infection: E.coli or Shigella

Children

Severe kidney problems

A

HUS

EOR: Family Medicine (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions