Eye Disorders: Pathophys/Etiology Flashcards
Eversion of eyelid and eyelashes
Ectropion
relaxation of _______ causes ectropion
orbicularis oculi
Inversion of eyelid and eyelashes
Entropion
Spasm of ______ may cause entropion
orbicularis oculi
Which is more common in elderly patients? Entropion or Ectropion
Entropion
Infection of lacrimal sac due to nasolacrimal duct obstruction
Dacrocystitis
4 Infectious agents that commonly cause dacrocystitis…
staph epidermis
staph aureus
GAS
Pseudomonas
Inflammation of the eyelid margin.
Can be posterior or anterior.
Blepharitis
Which type of blepharitis:
- Meibomian Gland Dysfunction
- MC Type of blepharitis
Posterior
2 types of anterior blepharitis:
infectious (staph aureus or epidermis)
seborrheic
______ blepharitis involves the skin and base of eyelashes
anterior
localized abscess of the eyelid margin…
Hordeolum
MC cause of hordeolum
Staph Aureus (90% of cases)
Painless indurated granuloma of internal Meibomian sebaceous gland
Chalazion
Chalazion is caused by obstruction of what gland(s)?
Zeis or Meibomian Glands
Slow growing thickening of bulbar conjunctiva consisting of fat, protein and calcium.
Pinguecula
Slow growing thickening of bulbar conjunctiva which starts medially
Pterygium
Disruption of the outer membranes of the eye due to blunt or penetrating trauma
911
Globe rupture
Fx of orbital floor due to blunt trauma
May lead to trapping of eye structures
Orbital Floor “Blowout Fx”
Orbital Floor consists of which 3 bones?
zygomatic, palatine, maxillary
4 types of orbital floor fx…
Inferior, Medial, Superior, lateral
Which type of orbital floor fx is MC?
Inferior (floor)
Which type of orbital floor fx?
orbital fat and/or inferior rectus prolapse into maxillary sinus
Inferior
Which type of orbital floor fx?
orbital fat and medial rectal prolapse into ethmoid air cells
Medial
Uncommon types of orbital floor fx…
superior/lateral
MC primary intraocular malignancy of childhood
Most dx before age 3
Retinoblastoma
2 types of retinoblastoma:
Non-heritable
heritable
Retinoblastoma is due to mutations in _____gene
RB1 gene
Which type of retinoblastoma may develop into bilateral retinoblastoma?
heritable
MC cause of permanent legal blindness and vision loss in older adults (75+ yo)
Macular Degeneration
2 types of Macular Degeneration
Dry (atrophic), Wet (neovascular/exudative)
Which type of macular degeneration is not as common, but more aggressive?
Wet (within months)
Which type of macular degeneration is MC type, and is progressive in nature?
Dry (over decades)
MC cause of new, permanent vision loss in 20-74 yo…
Diabetic Retinopathy
3 Types of diabetic retinopathy
nonproliferative, proliferative, maculopathy
Damage to the retinal blood vessels from longstanding high blood pressure…
hypertensive retinopathy
retinal detachment occurs when the retina separates from…
underlying retina pigment epithelium
3 Types of Retinal Detachment
Rhegmatogenous
Tractional
Exudative/serous
Which type of Retinal Detachment?
MC Type: full thickness tear
inner sensory layer detachment from choroid plexus
Rhegmatogenous
Which type of Retinal Detachment?
adhesion separate retina from base
caused by: sickle cell, trauma, proliferative diabetic retinopathy
Tractional
Which type of Retinal Detachment?
fluid accumulates beneath retina causing detachment
caused by: HTN, CRVO, Papilledema
Exudative
Neonatal conjunctival infection contracted by newborns during delivery
ophthalmia neonatorum
Day 1 cause of neonatal conjunctivitis:
chemical: silver nitrate
Days 2-5 cause of neonatal conjunctivitis:
MC gonococcal
Days 5-7 cause of neonatal conjunctivits
MC chlamydia trachomatis
MC causative agent of adult bacterial conjunctivitis
Staph aureus
Non Staph Aureus causes of bacterial conjunctivitis in adults (3)
Strep Pneumo, H. Flu, M. Catarrhalis
2 STIs that can cause adult bacterial conjunctivitis
gonorrhea, chlamydia
2 methods of transmission for bacterial conjunctivitis…
direct contact
autoinoculation
MC cause of viral conjunctivitis…
adenovirus
MC source of viral conjunctivitis during outbreaks…
swimming pools
viral conjunctivitis is trasmitted via…
direct contact
viral conjunctivitis is MC in…
children
in allergic conjunctivitis, allergen contact in eye causes __________ degranulation to release _________
mast cell degranulation
release histamine
What type of ocular chemical burn is worse, alkali or acidic?
alkali
Which type of ocular chemical burn?
causes liquefactive necrosis
denatures proteins
causes thrombosis of vessels
alkali burn
which type of ocular chemical burn?
causes coagulative necrosis
acid burns
misalignment of one or both eyes
strabismus
Convergent strabismus, deviation inward
esotropia
divergent strabismus, deviation outward
exotropia
stable ocular alignment not present until what age?
2-3mo
Orbital cellulitis is often what type of infection?
Polymicrobial
Orbital cellulitis is MC in what age group?
7-12 yo
Orbital cellulitis is MC as secondary infection after…
sinus infection (ethmoid sinus)
Infection of fat and ocular muscles posterior to orbital septum…
orbital cellulitis
infection of eyelid and periocular tissue anterior to orbital septum
preseptal/periorbital cellulitis
Corneal ulceration and/or inflammation
may be sight-threatening
Keratitis
What type of keratitis is increased in contact lens wearers?
pseudomonas aeruginosa
3 MC agents of keratitis…
staph aureus, streptococci, pseudomonas
Herpes keratitis occurs due to reactivation in the _________ ganglion.
Major cause of blindness in US
trigeminal ganglion
inflammation of the iris or ciliary body
Anterior uveitis
inflammation of the choroid
posterior uveitis
3 etiologies of uveitis
systemic inflammatory/autoimmune disease
infection
trauma
CMV, Toxoplasmosis, Syphilis can cause what eye infection?
uveitis
HLA-B27 spondyloarthropathies, sarcoidosis, IBD can cause what eye infection?
uveitis
lens opacification that is usually bilateral
Cataract
MC cause of blindness worldwide
cataract
optic nerve swelling due to increased ICP
papilledema
acute inflammatory demyelination of the opti nerve…
optic neuritis
Increased intraocular pressure leading to damage of optic nerve
leading cause of preventable blindness in the US
acute narrow angle-closure glaucoma
decreased drainage of aqueous humor via trabecular meshwork and canal of schlemm
acute narrow angle-closure glaucoma
slow, progressive, painless bilateral peripheral vision loss…
chronic/open angle glaucoma
rapid, painful unilateral vision loss
acute narrow angle-closure glaucoma
increased intraocular prssure due to reduced aqueous drainage through trabeculum
chronic/open angle glaucoma
transient monocular vision loss lasting minutes with complete recover
amaurosis fugax
transient blindness associated with retinal emboli or ischemia
amaurosis fugax
amaurosis fugax can be seen with what conditions (5)
TIA/Carotid Artery Disease Giant Cell Arteritis CRAO Migraine SLE
Retinal artery thrombus/embolus
911
central retinal artery occlusion
Central retinal artery occlusion is MC in what patient population?
MC 50-80 yo w. atherosclerotic disease
MC etiology of CRAO
emboli from carotid artery atherosclerosis
2nd MC cause of CRAO, but MC cause in young patients w/o atherosclerosis
cardiogenic emboli
thrombus in retinal vein leading to backup of fluid in retina
Central Retinal Vein Occlusion