Hematology

Question 2

Will the retic count be elevated, decreased or normal in a B12 deficient anemia?

Answer 2

Retic count will be low. Low building blocks means low production.

Question 3

G6PD deficiency follows what pattern of inheritance?

Answer 3

X- linked

Question 4

Will the RBC’s be large, small or normal size in a B12 deficient anemia?

Answer 4

Macrocytes

Question 5

Would a folic acid or B12 deficiency anemia most likely be microcytic, normocytic or microcytic?

Answer 5

Macrocytic

Question 6

Which anemia should you think of if you see the term Howell-Jolly bodies?

Answer 6

Sickle cell due to the functional asplenia, but may show up in folic acid deficiency

Question 7

Would anemia of chronic disease most likely be macrocytic, normocytic or microcytic?

Answer 7

Normocytic

Question 8

In iron deficient anemia will the serum ferritin be high or low?

Answer 8

It will almost always be low

Question 9

Asplenism secondary to sickle cell disease increases a patient’s risk for what type of infections?

Answer 9

Capsulated organisms like Strep pneumo and H. flu

Question 10

Stocking glove paresthesias should make you think of what two diagnoses?

Answer 10

B12 deficiency neuropathy and diabetic neuropathy

Question 11

In sickle cell disease unconjugated bilirubin will be elevated or decreased?

Answer 11

Elevated

Question 12

What is Schilling’s test used for?

Answer 12

Test for the cause of a B12 deficiency

Question 13

Iron deficiency anemia will have a serum iron lower than what value?

Answer 13

30

Question 14

Is sickle cell microcytic, macrocytic or normocytic?

Answer 14

Microcytic

Question 15

List the three diagnosis you should be thinking of if a question includes Heinz bodies.

Answer 15

G6PD deficiency anemia, chronic liver disease, alpha thalassemia

Question 16

What is the most common microcytic anemia?

Answer 16

Iron deficiency anemia

Question 17

Will a hemolytic anemia generally have an elevated or or decreased retic count?

Answer 17

Elevated

Question 18

What two main causes should you be thinking of in a macrocytic anemia?

Answer 18

Malnutrition and severe blood loss

Question 19

What is pica?

Answer 19

Eating non food items including ice, paper, dirt, hair

Question 20

You should be thinking alpha thalassemia if the question stem includes which four geographic areas?

Answer 20

Southeast Asia, China, Middle East, Africa

Question 21

List four disease states in which you may find basophilic stippling.

Answer 21

Lead poisoning, Beta or alpha thalassemia, sideroblastic anemia, arsenic poisoning

Question 22

Are target cells seen in mild or severe iron deficiency anemia?

Answer 22

Severe, they are also seen in alpha thalassemia, chronic liver disease and asplenia

Question 23

An African American teenager presents with avascular necrosis of the his right femoral head. What diagnosis should you be thinking of?

Answer 23

Sickle Cell disease

Question 24

A low retic count and a normal serum ferritin should make you think of what diagnosis?

Answer 24

Anemia of chronic disease

Question 25

Does an increase in reticulocytes indicate a decrease or an increase in RBC production?

Answer 25

An increase, reticulocytes are newly released “baby” RBC’s

Question 26

If a questions asks about anemia and pregnancy what is the likely diagnosis?

Answer 26

Iron deficiency

Question 27

Inability to absorb vitamin B12 due to lack of intrinsic factor is what disease?

Answer 27

Pernicious anemia

Question 28

Strict vegans are at risk for what type of anemia?

Answer 28

B12 deficiency anemia

Question 29

What molecule binds iron in the blood stream?

Answer 29

Transferrin

Question 30

What is the normal range for MCV?

Answer 30

80-100

Question 31

Auer rods a most commonly associated with what disease?

Answer 31

Acute Myeloid Leukemia

Question 32

The term Philadelphia chromosome you should make you think of what diagnosis?

Answer 32

Chronic myeloid leukemia

Question 33

How do you treat a sickle cell crisis?

Answer 33

Fluids, oxygen, pain medication, transfusion may be necessary

Question 34

Under normal conditions at what hemoglobin level would you begin to consider a transfusion?

Answer 34

8

Question 35

In a folic acid deficiency anemia the folic acid level is typically below what level?

Answer 35

<150

Question 36

A patient of mediterranean descent is a clue for which type of anemia?

Answer 36

Beta thalassemia

Question 37

What does koilonychia refer to?

Answer 37

Spoon shaped nails. This may be found in microcytic anemia

Question 38

What hematological disorder should you think of if the questions talks about the patient eating ice or dirt?

Answer 38

Iron deficiency anemia

Question 39

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Answer 39

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