Hematology Flashcards
Will the retic count be elevated, decreased or normal in a B12 deficient anemia?
Retic count will be low. Low building blocks means low production.
G6PD deficiency follows what pattern of inheritance?
X- linked
Will the RBC’s be large, small or normal size in a B12 deficient anemia?
Macrocytes
Would a folic acid or B12 deficiency anemia most likely be microcytic, normocytic or microcytic?
Macrocytic
Which anemia should you think of if you see the term Howell-Jolly bodies?
Sickle cell due to the functional asplenia, but may show up in folic acid deficiency
Would anemia of chronic disease most likely be macrocytic, normocytic or microcytic?
Normocytic
In iron deficient anemia will the serum ferritin be high or low?
It will almost always be low
Asplenism secondary to sickle cell disease increases a patient’s risk for what type of infections?
Capsulated organisms like Strep pneumo and H. flu
Stocking glove paresthesias should make you think of what two diagnoses?
B12 deficiency neuropathy and diabetic neuropathy
In sickle cell disease unconjugated bilirubin will be elevated or decreased?
Elevated
What is Schilling’s test used for?
Test for the cause of a B12 deficiency
Iron deficiency anemia will have a serum iron lower than what value?
30
Is sickle cell microcytic, macrocytic or normocytic?
Microcytic
List the three diagnosis you should be thinking of if a question includes Heinz bodies.
G6PD deficiency anemia, chronic liver disease, alpha thalassemia
What is the most common microcytic anemia?
Iron deficiency anemia
Will a hemolytic anemia generally have an elevated or or decreased retic count?
Elevated
What two main causes should you be thinking of in a macrocytic anemia?
Malnutrition and severe blood loss
What is pica?
Eating non food items including ice, paper, dirt, hair
You should be thinking alpha thalassemia if the question stem includes which four geographic areas?
Southeast Asia, China, Middle East, Africa
List four disease states in which you may find basophilic stippling.
Lead poisoning, Beta or alpha thalassemia, sideroblastic anemia, arsenic poisoning
Are target cells seen in mild or severe iron deficiency anemia?
Severe, they are also seen in alpha thalassemia, chronic liver disease and asplenia
An African American teenager presents with avascular necrosis of the his right femoral head. What diagnosis should you be thinking of?
Sickle Cell disease
A low retic count and a normal serum ferritin should make you think of what diagnosis?
Anemia of chronic disease
Does an increase in reticulocytes indicate a decrease or an increase in RBC production?
An increase, reticulocytes are newly released “baby” RBC’s
If a questions asks about anemia and pregnancy what is the likely diagnosis?
Iron deficiency
Inability to absorb vitamin B12 due to lack of intrinsic factor is what disease?
Pernicious anemia
Strict vegans are at risk for what type of anemia?
B12 deficiency anemia
What molecule binds iron in the blood stream?
Transferrin
What is the normal range for MCV?
80-100
Auer rods a most commonly associated with what disease?
Acute Myeloid Leukemia
The term Philadelphia chromosome you should make you think of what diagnosis?
Chronic myeloid leukemia
How do you treat a sickle cell crisis?
Fluids, oxygen, pain medication, transfusion may be necessary
Under normal conditions at what hemoglobin level would you begin to consider a transfusion?
8
In a folic acid deficiency anemia the folic acid level is typically below what level?
<150
A patient of mediterranean descent is a clue for which type of anemia?
Beta thalassemia
What does koilonychia refer to?
Spoon shaped nails. This may be found in microcytic anemia
What hematological disorder should you think of if the questions talks about the patient eating ice or dirt?
Iron deficiency anemia
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