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oral path 1 > hematologic disorders > Flashcards

hematologic disorders Flashcards

1
Q

lymphoid hyperplasia may effect

A

lymph nodes, waldeyer ring or oral lymphoid aggregates

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2
Q

where is waldeyers ring

A

oropharynx, soft palate, lat tongue, floor or mouth

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3
Q

acute and chronic lymphoid hyperplasia are

A

movable

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4
Q

tx for lymphoid hyperplasia

A

no tx

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5
Q

what do you include on your differential with lymphoid hyperplasia

A

lipoma and lymphoepithelial cyst

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6
Q

most common cause of anemia

A

iron deficiency

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7
Q

causes of iron dificiency

A

excessive blood loss, increased demands for RBCs, decreased intake, decreased absorption

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8
Q

oral findings of iron deficient anemia

A 
bald, burning tongue
erythema of oral mucosa
atrophy of filiform papillae
taste alteration
angular chelitis
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9
Q

what do you include in your differential with iron deficient anemia

A

acute erythematous candida

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10
Q

lab findings with iron deficient anemia

A

reduced hematocrit, serum iron is low

total iron binding capacity elevated

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11
Q

tx for iron deficient anemia

A

treat underlying cause

supplements

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12
Q

plummer vinson syndrome is characterized by

A 
iron deficient anemia
dysphagia
esophageal webs
koilonychia (spoon shaped fingernails)
scc
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13
Q

cause of pernicious anemia

A

deficiency of b12

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14
Q

what does b12 do in blood

A

catalyst for DNA synthesis, especially in bone marrow

results in fragile megaloblastic erythrocytes

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15
Q

oral manefestations of pernicious anemia

A

burning tongue, diffuse thining and erythema of oral mucosa, dorsum of tongue, usually candida

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16
Q

2 systemic factors for mucosal soreness or burning

A

anemia or nutritional deficiencies

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17
Q

2 local factors for mucosal soreness or burning

A

candidiasis

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18
Q

t/f. candidiasis is more common for a burning tongue than anemia

A

true

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19
Q

the radiographic hair on end appearance is characteristic of

A

sickle cell anemia and thalassemia

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20
Q

sickle cell anemia rbc characteristics

A

deformed, rigid, sickle shaped

less o2 carrying capacity

21
Q

marrow hyperplasia is due to

A

reduced function of rbcs

22
Q

in sickle cell and thalassemia marrow hyperplasia leads to

A

a periosteal reaction leading to interspersed trabeculae

23
Q

leukemias arise where

A

cells arise in bone marrow and spread to peripheral blood

24
Q

lymphomas arise where

A

in lymph nodes and other lymphoid tissue

25
Q

t/f white blood cells neoplasms are malignant

A

true

26
Q

t/f. acute lymphocytic leukemia is predominantly in adults

A

false, children

27
Q

clinical signs of leukemia

A

anemia (fatigue, shortness of breath), leukopenia, throbocytopenia (easy bleeding)
petechiae and pupura
spontaneous and prolonged gingival bleeding

28
Q

oral manefestations of leukemia

A 
extensive gingival ulceration
candidosis
herpetic infections (recurrent herpes)
gingival enlargement (infiltration of leukemic cells
29
Q

acute leukemia clinically looks like

A

gingival ulceration, necrosis, and enlargement

30
Q

where does hodgkins lymphoma usually begin

A

lymph nodes

31
Q

where is the most common presenting site of hodgkins lymphoma

A

head and neck

32
Q

most cases of hodgkin lymphoma show enlargement of which nodes

A

cervical and supraclavicular lymph nodes

33
Q

reed sternberg cells

A

malignant cells of hodgkins lymphoma

34
Q

t/f hodgkin lymphoma can have cervical lymphadenopathy

A

true

35
Q

non-hodgkins usually originated from this type of wbc

A

b cells

36
Q

t/f burkitts is usually a childrens disease

A

true

37
Q

if untreated, burkitts can kill a pt in how many weeks

A

4-6 weeks

38
Q

tx for burkitts

A

intensive chemotherapy

39
Q

plasmacytoma radiographically presents as

A

a scooped out bone appearance

40
Q

multiple myeloma is a malignancy of what type of cells

A

plasma cells

41
Q

characteristics of multiple myeloma

A

bone pain, pathological fractures, fatigue (anemia), fever (neutropenia)

42
Q

well punched out radiolucent lesions are associated with what disease

A

multiple myeloma

43
Q

bence jones proteins

A

m-protein found in serum or urine of pts with multiple myeloma

44
Q

eosiniphilic granuloma

A

langerhans cells disease with one radiolucent area

45
Q

chronic disseminated histiocytosis

A

langerhans cells disease with bone lesions, exophthalamus, DI

46
Q

langerhans has a radiographic appearance of

A

a scooped out appearance with “teeth floating in the air”

looks like periodontitis with alveolar bone loss

47
Q

3 types of langerhans cell diseases

A

eosiniphilic granuloma, chronic and acute disseminated histiocytosis

48
Q

t/f burkitts lymphoma has the starry sky appearance

A

true

oral path 1 (11 decks)

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