Heavy metals: Zinc Dr. Bergfelt Flashcards
1
Q
MoA of Zinc Toxicity
A
May cause hemolytic anemia →hemoglobinemia & hemoglobinuria
hemolysis
2
Q
CS of zinc toxicity
A
GIT (cellular irritation/damage): vomiting, anorexia, lethargy, diarrhea
Hematologic (RBC damage): hemolytic anemia, icterus,
Renal (cell damage):Azotemia, hyperphosphatemia
3
Q
Chem analysis for zinc
A
Use trace element tubes for analysis
Royal/dark blue tube stopper
serum, liver kidney, pancreas, urine
4
Q
What would you expect to see with zinc toxicity?
A
Hemolytic anemia
5
Q
Ddx with zinc toxicity
A
Other toxins that can cause hemolytic anemia:
Copper, lead toxicosis
naphthalene toxicosis
onion poisoning
6
Q
Tx for zinc toxicity
A
decontamination
supportive care
Chelation?
-Calcium disodium EDTA chealator
