Heart Failure Medications Flashcards
Cardiac Glycoside: Prototypes
digoxin [Lanoxin]
Cardiac Glycoside: EPA
Positive inotropic effect that improves the contractility of the heart and its ability to pump.
Cardiac Glycoside: Therapeutic Use
Management of mild to moderate heart failure in adults and children. The drug is used to control the ventricular response rate in adults with atrial fibrillation.
Cardiac Glycoside: ADRs
Very narrow window as its very toxic. But the main ADRs are cardiac dysrhythmias.
Cardiac Glycoside: Contraindications
Avoid with:
Infants, children, and older adults as the risk for toxicity is increased.
Clients with ventricular dysrythmias and AV blocks
Sympathomimetics: Prototypes
dobutamine
Dopamine [Powerpoint notes section]
Sympathomimetics: Therapeutic Use
Severe heart failure [short term use]
Sympathomimetics: EPA
Beta 1 adrenergic agonist. Results in increased cardiac outpost
Sympathomimetics: ADR
tachycardia, dysrhythmias, and anginal pain
Sympathomimetics: Contraindications
MAOI and Tricyclics. ANtidepressants and General anesthesia.
Phosphodiesterase Inhibitor: Prototype
milirone
Phosphodiesterase Inhibitor: Therapeutic Use
Short term management of acute to severe heart failure patients.
Also used in patients who are not responsive to digoxin, diuretics, and vasodilartos.
Phosphodiesterase Inhibitor: EPA
Blocks PDE3 [phosphodiesterase] which is an enzyme responsible for breaking down adenosine monophosphate. Results in a positive inotropic effect
Phosphodiesterase Inhibitor: ADR
Ventricular dysrthmias
Hypotension, Hypokalemia, chest pain [angina]
Phosphodiesterase Inhibitor: Contraindications
Caution with aortic and pulmonary valve issues [also MIs]
Caution with renal impairments, electrolyte imbalances [monitor K+ on this one], renal impairment and abnormal digoxin levels.
