Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology chapter 6 > HEART FAILURE > Flashcards

HEART FAILURE Flashcards

1
Q

What happen to the cardiac output and demand of heart failure

A

👇🏻cardiac output

☝🏻️demand from the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the sign and symptoms in the right sided heart failure

A

Peripheral edema

Neck vein engorgement

Hepatomegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happen in the left side HF

A

Pulmonary edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the other sign and symptoms

A

Orthopenia

Dyspnea on exertion

Paroxymal nocturnal dysypnea

Third heart sound

Cardiomegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Heart failure is…

A

Pump/mechanical failure

Inability of the heart to contract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the NYHA functional classes

A

Class 1,2,3,4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the meaning of class 1 NYHA

A

Dyspnea on greater than ordinary activities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the meaning of class 2 NYHA

A

Dyspnea on ordinary activities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the meaning of class 3 NYHA

A

Dyspnea on less than ordinary activities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the meaning of class 4 NYHA

A

Dyspnea at rest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is dyspnea

A

Difficult respiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Approach to mngt of HF

A

☝🏻️ strength of contraction

👇🏻cardiac workload

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What drugs should be use to ☝🏻️the strength of contraction

A

Inotropics
👉🏻cardiac glycoside
👉🏻B1 agonist
👉🏻phosphodiesterase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drugs should be use to 👇🏻cardiac workloads

A 
Unloaders
    👉🏻ACEi ARBS
    👉🏻Diuretics 
    👉🏻vasodilators 
    👉🏻Beta blockers
    👉🏻BNP analogue
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the meaning of orthopnea

A

Shortness of breath when supine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the MOA of cardiac glycoside

A

Inhibit Na/K ATPase Pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the effects in Cardiac glycoside

A

(+) inotropism
(-) cronotropism
(-) dromotropism

18
Q

What are the drugs in Inotropic agents Cardiac Glycoside

A

Digoxin (lanoxin)

Digitoxin

19
Q

Do not give digoxin if…

A

👇🏻HR

Hypokalemia

Hypomagnesemia

Quinidine

HYPERcalcemia

20
Q

What are the differences of digoxin in digitoxin in oral BA

A

Digoxin 👉🏻 70-75%

Digitoxin👉🏻 >90%

21
Q

What are the differences of digoxin in digitoxin in serum t1/2

A

Digoxin👉🏻36-40hrs

Digitoxin 👉🏻168hrs

22
Q

What are the differences of digoxin in digitoxin in protein binding

A

Digoxin👉🏻20-40%

Digitoxin 👉🏻>90%

23
Q

What are the differences of digoxin in digitoxin in volume of distribution

A

Digoxin 👉🏻 6.3L/kg

Digitoxin 👉🏻 0.6L/kg

24
Q

What are the differences of digoxin in digitoxin in elimination

A

Digoxin👉🏻 kidney

Digitoxin 👉🏻Liver

25
Q

What are the signs having digoxin toxicity or narrow therapeutic index

A

GIT

Blurred vision

Arrythmia

26
Q

What is the DOC in digoxin toxicity

A

Digibind

Immunefab

27
Q

DOC for cardiac glycoside induce arrythmia

A

Lidocaine

28
Q

What are the drugs in Inottopic agents B1 agonist

A

Dopamine

Dobutamin

29
Q

What is the MOA of b1 agonist

A

Stimulates adenylyl cyclase

30
Q

What are the drugs use in Inotropic agents Bypyridines

A

Milrinone

Amrinone

31
Q

What is the use of B1 agonist combined with Bipyridines

A

Mgt of acute HF and acute exacerbation of chronic HF

32
Q

Unloaders should be given with combination

A

Of other unloaders or inotropics

33
Q

Unloaders decreases..

A

👇🏻preload / afterload

👇🏻 cardiac workload

34
Q

ACEi and ARBs decreases and increases??

A

👇🏻preload and after load

👇🏻aldosterone

👆🏻 Na and H20 excretion

35
Q

ACEi should be..

A

Use the maximum tolerable or allowable dose

Titrate the dose

36
Q

What is the MOA of BNP analogue

A

Massive vasodilators

37
Q

What is the meaning of BNP analogue

A

Brain natriuretic peptide analogue

38
Q

Vasodilators are recommended in the ff situation

A

Px is africant descent

When acei arbs cannot be given

39
Q

What are the drugs in vasodilators

A

ISDN + hydralazine

40
Q

Which one 👇🏻preload in vasodilators drugs

A

ISDN

41
Q

Which one 👇🏻afterload in vasodilators drugs

A

Hydralazine

Pharmacology chapter 6 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions