ANGINA PECTORIS

Question 1

Angina pectoris

Answer 1

Chest pain / discomfort caused by myocardial ischemia

Mismatch O2 supply and Demand

Question 2

Infaction

Answer 2

NO O2

Question 3

Ischemia

Answer 3

👇🏻O2

Question 4

Disease

Answer 4

Coronary artery disease

Question 5

Pathophysiology

Answer 5

Atherosclerosis

Build up clot

Question 6

Manifestation of Coronary Artery disease

Answer 6

• Acute coronary syndrome
• Chronic stable angina pectoris
• Prinzmetal angina

Question 7

Acute manifestation CAD

Answer 7

-Acute coronary syndrome

Question 8

Types of acute coronary syndrome

Answer 8

Acute MI
  -STEMI =occlusive
  -NSTEMI=non occlusive
Unstable Angina Pectoris
  -Rest Angina
  -crescendo
  -new onset

Question 9

Acute MI

Answer 9

☝🏻️cardiac biomarkers
Troponin
CK

Question 10

Unstable Angina Pectoris

Answer 10

(-)Cardiac Biomarkers

Question 11

STEMI? And indicate the drugs

Answer 11

Completely block

• Fibrinolytics
• anticoagulant

Question 12

NSTEMI? And what drugs

Answer 12

Partially block

Anticoagulants

Question 13

Chronic stable angina pectoris

☝🏻️ O2 _____?

Answer 13

☝🏻️O2 demand

Question 14

Vasopasm

Answer 14

Prinzmetal angina

Question 15

Aprroach to managemt

Answer 15

☝🏻️O2 supply

👇🏻O2 demand

Question 16

Give mngt in ☝🏻️O2 supply

Answer 16

• percutaneous transluminal coronary angioplasty
• coronary artery bypass grafting
• coronary vasodilators

Question 17

Give the mngt in 👇🏻O2 demand

Answer 17

• nitovasodilators
• beta blockers
• CCB’s

Question 18

What happen if the O2 demand 👇🏻

Answer 18

👇🏻HR
👇🏻SV
👇🏻SVR

Question 19

What is the MOA of nitrovasodilators

Answer 19

☝🏻️NO but requires SH group

Question 20

What are the effects that may occur in nitrovasodilators having a Low dose

Answer 20

Peripheral venodilation

👇🏻preload
👇🏻O2 demand

Question 21

What are the effects that may occur in nitrovasodilators having a High dose

Answer 21

Arteriolar vasodilation

☝🏻️O2 supply

Question 22

What is the SE in high dose nitrovasodilators

Answer 22

Reflex tachycardia

☝🏻️O2 demand

Question 23

What is the remedy in high dose in nitrovasodilators

Answer 23

Beta blockers

Question 24

Drugs in nitrovasodilators

Answer 24

Very short acting
Short acting
Intermediate acting
Long acting agents

Question 25

Very short acting

Duration

Answer 25

Amyl nitrite

<5-10mins

Question 26

Short acting agents

Duration

Answer 26

NTG
ISDN

10-30mins

Question 27

Intermediate acting

Duration

Answer 27

NTG SR tab
ISDN po tab

5-8hrs

Question 28

Long acting agents

Duration

Answer 28

NTG transdermal patch
ISDN SR tab
ISMD po tab

10-24hrs

Question 29

SE of nitrovasodilators

Answer 29

Hypotension
Migraine like HA
Tolerance
Methemoglobinemia

Question 30

Beta blockers

Answer 30

DOC OF CSAP

Question 31

Calcium channel blocker

Answer 31

(Non DHP)

DOC FOR PRINZMETAL
ALT. CSAP

Question 32

How many minutes of acute coronary syndrome occur in chest pain

Answer 32

20 mins

Question 33

Chronic stable angina pectoris how many minutes chestpain

Answer 33

Chest pain 2-5 mins during or after physical exertion and emotional stress

Question 34

Chronic manifestation of CAD

Answer 34

CSAP

Question 35

Prinzmetal angina 👇🏻 what?

Answer 35

👇🏻O2 supply

Question 36

Mngt of acute coronarysyndrome

Answer 36

IV infusion

Question 37

Mngt of CSAP

Answer 37

PO or Trandermal

Question 38

Mngt of prinzmetal

Answer 38

IV infusion + beta blockers

Question 39

Mngt of HF

Answer 39

Hydralazine + ISDN

Question 40

Alternative in mngt of HTN emergencry crisis

Answer 40

IV infusion

Question 41

What MOA is sildenafil

Answer 41

(-) phosphodiesterase

Question 42

SE of sildenafil

Answer 42

Hypotension

Migraine like HA

Tolerance