ANGINA PECTORIS Flashcards

1
Q

Angina pectoris

A

Chest pain / discomfort caused by myocardial ischemia

Mismatch O2 supply and Demand

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2
Q

Infaction

A

NO O2

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3
Q

Ischemia

A

πŸ‘‡πŸ»O2

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4
Q

Disease

A

Coronary artery disease

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5
Q

Pathophysiology

A

Atherosclerosis

Build up clot

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6
Q

Manifestation of Coronary Artery disease

A
  • Acute coronary syndrome
  • Chronic stable angina pectoris
  • Prinzmetal angina
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7
Q

Acute manifestation CAD

A

-Acute coronary syndrome

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8
Q

Types of acute coronary syndrome

A
Acute MI
  -STEMI =occlusive
  -NSTEMI=non occlusive
Unstable Angina Pectoris
  -Rest Angina
  -crescendo
  -new onset
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9
Q

Acute MI

A

☝🏻️cardiac biomarkers
Troponin
CK

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10
Q

Unstable Angina Pectoris

A

(-)Cardiac Biomarkers

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11
Q

STEMI? And indicate the drugs

A

Completely block

  • Fibrinolytics
  • anticoagulant
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12
Q

NSTEMI? And what drugs

A

Partially block

Anticoagulants

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13
Q

Chronic stable angina pectoris

☝🏻️ O2 _____?

A

☝🏻️O2 demand

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14
Q

Vasopasm

A

Prinzmetal angina

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15
Q

Aprroach to managemt

A

☝🏻️O2 supply

πŸ‘‡πŸ»O2 demand

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16
Q

Give mngt in ☝🏻️O2 supply

A
  • percutaneous transluminal coronary angioplasty
  • coronary artery bypass grafting
  • coronary vasodilators
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17
Q

Give the mngt in πŸ‘‡πŸ»O2 demand

A
  • nitovasodilators
  • beta blockers
  • CCB’s
18
Q

What happen if the O2 demand πŸ‘‡πŸ»

A

πŸ‘‡πŸ»HR
πŸ‘‡πŸ»SV
πŸ‘‡πŸ»SVR

19
Q

What is the MOA of nitrovasodilators

A

☝🏻️NO but requires SH group

20
Q

What are the effects that may occur in nitrovasodilators having a Low dose

A

Peripheral venodilation

πŸ‘‡πŸ»preload
πŸ‘‡πŸ»O2 demand

21
Q

What are the effects that may occur in nitrovasodilators having a High dose

A

Arteriolar vasodilation

☝🏻️O2 supply

22
Q

What is the SE in high dose nitrovasodilators

A

Reflex tachycardia

☝🏻️O2 demand

23
Q

What is the remedy in high dose in nitrovasodilators

A

Beta blockers

24
Q

Drugs in nitrovasodilators

A

Very short acting
Short acting
Intermediate acting
Long acting agents

25
Q

Very short acting

Duration

A

Amyl nitrite

<5-10mins

26
Q

Short acting agents

Duration

A

NTG
ISDN

10-30mins

27
Q

Intermediate acting

Duration

A

NTG SR tab
ISDN po tab

5-8hrs

28
Q

Long acting agents

Duration

A

NTG transdermal patch
ISDN SR tab
ISMD po tab

10-24hrs

29
Q

SE of nitrovasodilators

A

Hypotension
Migraine like HA
Tolerance
Methemoglobinemia

30
Q

Beta blockers

A

DOC OF CSAP

31
Q

Calcium channel blocker

A

(Non DHP)

DOC FOR PRINZMETAL
ALT. CSAP

32
Q

How many minutes of acute coronary syndrome occur in chest pain

A

20 mins

33
Q

Chronic stable angina pectoris how many minutes chestpain

A

Chest pain 2-5 mins during or after physical exertion and emotional stress

34
Q

Chronic manifestation of CAD

A

CSAP

35
Q

Prinzmetal angina πŸ‘‡πŸ» what?

A

πŸ‘‡πŸ»O2 supply

36
Q

Mngt of acute coronarysyndrome

A

IV infusion

37
Q

Mngt of CSAP

A

PO or Trandermal

38
Q

Mngt of prinzmetal

A

IV infusion + beta blockers

39
Q

Mngt of HF

A

Hydralazine + ISDN

40
Q

Alternative in mngt of HTN emergencry crisis

A

IV infusion

41
Q

What MOA is sildenafil

A

(-) phosphodiesterase

42
Q

SE of sildenafil

A

Hypotension

Migraine like HA

Tolerance