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Pharmacology chapter 6 > ANTI-ARRYTMIA > Flashcards

ANTI-ARRYTMIA Flashcards

1
Q

Arrythmia

A

Bradycardia

Tachycardia

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2
Q

Phase 4

A

Resting phase

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3
Q

Phase 0

A

Depolarization

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4
Q

Phase 1

A

Repolarization

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5
Q

Phase 2

A

Plateau phase

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6
Q

Phase 3

A

Repolarization

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7
Q

Phase 4 channels

A

Negatively charged

Opening K channels

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8
Q

Phase 0 channels

A

Close K

Open Na

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9
Q

Phase 1 channel

A

Open K

Close Na

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10
Q

Phase 2 channels

A 
Open K (palabas)
Open Na(papasok)
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11
Q

Phase 3 channels

A

Open K

Close Cl

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12
Q

Therapeutic goals in Mgt. of arrythmia

A

Na channel blockade(phase2)

Inh. Of sympathetic innervation in the heart

Prolangation of effective refractory period

CCB

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13
Q

Vaughn williams classification of drugs

A

Class1 - Na channel blocker
Class2 - beta blocker
Class3 - K channel blocker
Class4 - Ca channel blocker

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14
Q

What are the rhythm disorder

A
  • Atrial fibrillation
  • Paroxymal supraventricular tachycardia
  • ventricular tachycardia
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15
Q

P wave

A

Atrial DEPOlarization

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16
Q

P-R wave

A

Allow ventricular filling

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17
Q

QRS wave

A

Ventricular DEPOlarization

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18
Q

ST wave

A

Gradual REPOlarization

19
Q

T wave

A

Ventricular REPOlarization

20
Q

Atrial fibrillation

A

No P wave

R-R interval are not equal

21
Q

Blood stasis in the atria

A

Thrombosis

Stroke

22
Q

Chronic AF

A

Warfarin

ASA for prophylaxis

23
Q

SVT HR

24
Q

SVT normal tachycardia

25
Q

Forms of SVT

A

AV nodal reentrant tachycardia

AV reentrant tachycardia

26
Q

Forms in vetricula tachycardia

A

Monomorpgic VT
–one size & shape

Polymorphic VT
–diff. Size &shape

27
Q

QRS predominant

A

Ventricular tachycardia

Fatal

28
Q

What are the types of class1 - Na channel blocker

A

Class 1a
Class 1b
Class 1c

29
Q

Prolongs the action potential

30
Q

Shortens the action potential

31
Q

No action potential

32
Q

Uses of class1a

33
Q

AE of class1a

A

R on T wave

Procainamide- drug induced lupus

Quinidine- 👇🏻excreation of digoxin
☝🏻️ digitalis toxicity

34
Q

Drugs for class 1b

A

Tocainide
Mexilitine
Lidocaine
Phenytoin

35
Q

Uses of lidocaine

A

DOC FOR DIGITALIS TOXICITY

mgt of VT in px with post AMI

36
Q

Drugs dor class1c

A

Moricizine
Flecainide
Propafenone
Encainide

37
Q

AE of class1c

A

VT

Atrial flutter

38
Q

Drugss for class2 beta blocker

A

Propanolol
Esmolol
Atenolol

39
Q

Class3 k channel blocker drugs

A 
Amiodarone
Bretylium
Sotalol
Ibutilide
Dofetilide
40
Q

Uses of class3 K channel blocker

41
Q

SE of class3

A

Thyroid dysfunction
Hepatotoxicity
Pulmonary fibrosis

42
Q

Class 4 Ca channel blocker

A

Non DHP

DOC of the maintenance tx of paroxymal SVT alternative tx for acute VT

43
Q

Adenosine

A

DOC ACUTE VT

Pharmacology chapter 6 (8 decks)

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