Heart failure Flashcards
1
Q
Why are drugs not given orally in patients w HF?
A
gut absorption is poor due to sympathetic NS activation which shunts blood away from gut to heart + brain so IV admin better
2
Q
MoA of Thiazide diuretics
A
block Na+/Cl- cotransporter in distal convoluted tubule
3
Q
Eplerenone
A
selective aldosterone antagonist