Heart Flashcards

1
Q

What does the cardiovascular system consist of ?

A

heart, blood and blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How many times des the heart beats?

A

100k times per day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How many times does the heart beat per lifetime?

A

2.9 Billion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How many circuits is the heart lined with the CV system ?

A

2 Main circuits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Carries blood to and from the lungs to the heart

A

Pulmonary Circuit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Transports blood to and through the body (heart to tissues and back to the heart

A

Systemic circuit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Arteries carry blood ?

A

Away from heart and towards tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Veins to heart

A

Away from tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Great Vessels

A

Largest veins and arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Capillaries

A

Smallest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How many chambers does the heart has? (cut half of the coronal plane)

A

4 chambers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Left atrium and Left ventricles

A

L- atrium collects blood from pulmonary circuit dumps into L- ventricle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

R- atrium collects blood from __ and dumps into ___

A

systemic circuit; R- ventricle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What contracts first in the heart then what ?

A

The atria’s contract first, then ventricles.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What’s the outer muscle of the heart?

A

Epicardium ( Visceral pericardium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What’s the middle muscle of the heart?

A

Myocardium - spiral bundles of muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What’s the inner muscle of the heart?

A

Endocardium ( simple squamous cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Outer _____ pericardium prevents overfilling. helps to protect

A

Fibrous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

The heart is surrounded by ____ to protect it from friction ?

A

pericardial sac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Inner ____ pericardium

A

Serous
Outer parietal layer, inner visceral layer (epicardium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Increases fluid in pericardial space when infected

A

Pericarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Deep groove on the border between atria/ventricles

A

Coronary Sulcus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Expandable extension of the atrium “ Ear-like”

A

Auricle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

The posterior interventricular sulcus contains ?

A

Fat pads (stripped to see cardiac vessels)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
The Anterior interventricular sulcus is the ???
Boundary between L and R ventricles
19
What type of tissue is the Myocardium?
Connective tissue of the heart
20
Cells are wrapped in elastic sheath- adjacent cells crosslinked
-Provide physical support -Distributes force of contractions -Prevent overextension -Provides recoil effect
20
Ventricles are separated by ?
Atrioventricular septum--- Big muscle right in the middle
21
What separates the atriums?
Thinner Inter-atrial septum
22
What valve separates the atriums from their ventricle ??
Atrioventricular valve
23
what valve is in the Right atrium?
Tricuspid valve
24
This valve is in the Left atrium
Mitral (bi-cuspid valve)
25
There are one-way valves to help direct blood flow and prevent backflow and to ensure proper pressure and gradient flow
26
Located in between the aorta and L ventricle and pulmonary vein and R ventricle
Semilunar valves
27
What muscle is on the posterior right side of the atrium and interatrial septum?
Pectinate muscles
28
What muscle arises from the ridges to to anchor the chordae tendinea whose job is to pull on the tricuspid valve and bicuspid valve?
Papillary muscle
29
This section -muscle ridges- prevents overdistention, increased performance, prevents suction.
Trabeculae Carneae
30
What Atrium receives blood from superior and inferior vena cava
Right Atrium
31
From Head, neck, upper limbs, and chest
Superior vena cava
32
Trunk, viscera lower limbs
Inferior vena cava
33
____ connects L and R atriums in embryonic stages- closed at birth- left over depression called _____
Foramen Ovale; Fossa Ovalis
34
What atrium receives blood from L and R pulmonary veins?
Left Atrium
35
Why does blood move from atrium to ventricles ?
trabeculae carnae are more prominent
36
Ventricle muscle is much thicker on ???
Left than Right because contractile force is needed
37
This valve prevents backflow into the atrium from ventricles ?
Atrioventricular valves
38
Ventricle contraction causes papillary muscle contraction and the AV valves swing closed to prevent backflow- chordae tendinea tense- prevents AV valves from swinging up into atria
Regurgitation
39
This valves don't need chords no contraction- 3 flaps support each other like a stool
Semilunar valves
40
The right atrium receives blood from?
Superior and inferior vena cava
41
The left atrium receives blood from ??
The 2 pulmonary veins
42
deliver blood to the heart itself and arise from the base of the aorta
Coronary arteries
43
BP is highest in
aorta and systemic circuit
44
R and L coronary arteries originate at the R and L aortic sinuses to give blood to
myocardium
45
R - coronary artery follows coronary sulcus around the heart  supplies blood to:
-R atrium -Both ventricles -Conducting system of heart
46
L coronary artery supplies to
- L - Ventricle - L - Atrium - Interventricular septum
47
Branching off from the L- coronary artery is the
circumflex and LAD
48
_______Connects L to R as to prevent de-oxygen if one side gets damaged
Circumflex artery
49
runs along the surface of the interventricular surface
Left Anterior Descending Interventricular artery (LAD)
50
Connections like circumflex are called?
Anastomoses
51
begins on the anterior (front) portion the heart following the interventricular sulcus; Drains blood from the LAD
Great Cardiac Vein
52
drains the myocardium
Coronary Sinus
53
What are the 2 Heart specialized cells
Autorhythmic (pacemaker) cells and Contractile (cardiac cells)
54
Control and coordinate heartbeat – contain their own electrical current (no true resting membrane) - sinoatrial node, atrioventricular node, atrioventricular bundle, L/R bundle branches and purkinje fibers (in this order)
Autorhythmic (pacemaker) cells
55
sinoatrial node, atrioventricular node
Nodal Cells
56
Originates in the Posterior wall of the R- atrium. - Generates “sinus rhythm” (60-80 beats per minute) - Sends projections to L atrium  Bachmus bundle
Sino-Atrial node (SA)
57
sends fiber to interventricular septum and continues the transfer of the depolarization -Takes 0.1 second delay to allow time for each atria to contract - Less gap junctions b.) Conducting cells additnally make up the atrioventricular bundle, L/R bundle branches and purkinje fibers i.) Connect the SA and AV nodes/ propagate signals to the contractile tissue of the heart
Atrio-Ventricular node (AV)
58
produce power propelling blood a.) Action potential flows through the heart tissue causing contraction
Contractile (cardiac) cells
59
Damage to conducting pathways result in ?
conducting deficits (reduce BPM)
60
Abnormal conduction outside the SA and AV nodes is an
ectopic pacemaker (disrupts timing)
61
At threshold Na+ rushes in due to “fast” Na+ channels
(Phase 0) Rapid Depolarization
62
K+ leaks out of contractile cells causing a drop in voltage. This activates Ca2+ channels.
(Phase 1) Plateau
63
Ca2+ influx and K+ outflow continues giving the voltage plateau phase. b.) Together they 1. Delay repolarization and 2. Keeps membrane potential at 0mV for extended period  long to aid in contraction c.) Cells contract similar to muscle cells: action potential transferred via T- tubules, activation of sarcoplasmic reticulum, release of calcium, binds to troponin and allow myosin and actin to cause a power stroke
(Phase 2)
64
Ca2+ channels in the contractile cell now close; due to reduced cation transportation from repolarization of nodal cells. More K+ channels now open and more K+ leaves the cell.
(Phase 3) Repolarization
65
cells won’t respond to another impulse: 1. Absolute refractory period (no stimulus can cause depolarization) and 2. Relative refractory period (a strong signal can cause depolarization) 6.) To depolarize you need the three fundamental ions (similar to muscles) Na+, K+, and Ca2+ 7.) Heart needs to contract for longer - Ca2+ helps sustain/prolong the contraction.
(Phase 4) Refractory Period
66
When the atria depolarize as a result of the SA node actions on the heart tissue you get the
“P” wave
67
When the ventricles (both of them) contract to push blood in their respective systems you get the
“QRS” wave
68
where the ventricles contract and atrial repolarization takes place (but cannot see)
The “R” wave
69
When the ventricles repolarize is when the you get the?
“T” wave
70
Extend from the end of the wave to the beginning of the next
Segments
71
Variable and include at least one wave
Intervals
72
atrial depolarization to the start of QRS complex (extensions more than 200msec indicate damage to AV or conducting pathways)
P-R interval
73
an be lengthened by electrolyte, medication, conducting problems
Q-T interval (single re/de-polarization)
74
99% of the atrial and ventricle walls are made up of
cardiac/contractile cells
75
contraction of chamber (atrium, ventricle)
Systole
76
relaxation of chamber (Filling with blood occurs here)
Diastole
77
BP rises in___ and decreases in ___ (high to low)
Systole; Diastole
78
begins with topping off the ventricles contracting to push 30% of remaining bloods into ventricles
Atrial systole
79
no blood enters as pressure is higher than in veins
Atrial diastole
80
ullest amount of blood in ventricles in cardiac cycle (occurs after atrial systole and before ventricles contract)
End-Diastolic Volume
81
is the contraction (without moving blood) generating pressure and tension - not yet strong enough to push the blood out.
Isovolumetric contraction
82
occurs next finally reaching threshold for pressure to eject blood out into the aorta and pulmonary vein
Ventricle Systole
83
Amount of blood left in the ventricles after semilunar valves close (less than EDV)
End-Systolic Volume
84
now occurs where all valves are closed and myocardium relaxes regaining threshold from action potential
Ventricle Diastole
85
ventricle pressure still greater than atrial pressure - nothing flows into ventricles called
Isovolumetric relaxation
86
Semilunar valves opening/ AV valves closing
Lubb
87
Semilunar valves close/ AV valves open
Dubb
88
The number of beats per minute and is affected by hormones and/or CNS
Heart Rate
89
Is the amount of blood pumped out the ventricle during each contraction  SV = EDV - ESV
Stroke Volume
90
Is the amount of blood which leaves the left ventricle in one minute  CO (mL/minute) = HR (Beat/minute) x SV (mL/beat)
Cardiac Output
91
is nerve network of the heart and is the connection point for the SNS where NE is released.
Cardiac Plexus
92
Cardiac centers in brain control rate
cardioinhibitory and cardioacceleratory (nuclei in the medulla oblongata)
93
Degree of stretching in ventricle muscle cells during ventricle diastole  high EDV = high preload
Preload
94
is amount of blood that returns/reaches atria  more means increased heart rate
Venous return
95
a.) Filling Time – decides preload and is the duration of ventricle diastole (faster heart rate = shorter filling time)
Factors affecting EDV:
96
Increased stretch beyond optimal length reduces force of contraction a.) Greater stretch = greater contraction = preload
Frank-Starling Principle
97
atrial reflex) occurs when the heart rate increases in response to a rise in atrial pressure. This is a compensatory mechanism since increased right atrial pressures frequently result from elevated left heart pressures from decreased cardiac output.
Bainbridge reflex
98
Preload
factor affecting ESV
99
b.) Ventricular contractility – Amount of force produced during a contraction at a given preload  SNS, T4/3, Glucagon, Drugs, Ions, Acidosis
One factor affecting ESV
100
Afterload - Amount of tension that the contracting ventricle must produce to force open the semilunar valve and eject blood (aka amount of resistance that must be overcome)
factor affecting ESV
101
High afterload
Low stroke volume
102
Vasodilatation (_________afterload) and vasoconstriction (__________ afterload, ex; aortic valve dysfunction, plaque, HBP)
Decreases; increases
103
SA node, SNS, PNS, T4/3, Body Temp, Ions, partial pressure of CO2 and Oxygen, age, fitness
Factors affecting HR
104
Maximal cardiac output - Resting cardiac output
Cardiac Reserve
105
Trained athletes increase _____ by 700% (limit to increase)
cardiac output
106
weakening of left ventricle after a loss or extreme stress – ECGs and blood enzymes resemble heart attacks!
Broken Heart Syndrome (Takotsubo cardiomyopathy)
107
If the heart was merely a pump it would take roughly 1 million times the strength to push the blood through the system  use
water hydrodynamics to circulate
108
When we evaluate heart’s muscle itself, we find it is wrapped in a helical way causes_____
toroidal field
109
i.) Muscular milking (valves) ii.) Respiratory pump (High to low) iii.) Venomotor Constriction via SNS c.) Myocardial Infarction – reduce preload
Factoring increasing venous return: