Health and Disease KQ2 and KQ3 (Malaria) Flashcards

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1
Q

What and how Malaria is transmitted?

A
  • Life-threatening parasite induced disease
  • Vector-borne via Anopheles female mosquito

1) Mosquito takes bloodmeal w/ malaria parasite
2) Parasite breeds in mosquito
3) Mosquito injects parasite into healthy person
4) Parasite infects person, moves to liver to reproduce and spread into bloodstream

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2
Q

Extent and spread of Malaria

A
  • Spread via expansion diffusion
  • Endemic in tropics and sub-tropics
  • Can occur in non-endemic countries when infected person travels
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3
Q

Malaria in Africa

A
  • 90% malaria deaths occur in Africa
  • African mosquitoes have longer lifespan, prefer to feed on human blood than animal blood
  • Higher incidence of malaria = higher mortality rates
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4
Q

Groups vulnerable to Malaria

A

1) 50% world population live in areas endemic to Malaria
2) Pregnant women and young children
3) Immuno-compromised individuals

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5
Q

Factors contributing to spread of Malaria

A

> Socio-economic
1) Lack of proper sanitation
2) Overcrowded living conditions
3) Limited provision and access to HC

> Environmental
1) Poor drainage and stagnant water
2) Effect of climate

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6
Q

SEF: Lack of proper sanitation

A
  • Waste water not disposed of
  • Forms stagnant water pools
  • Favourable breeding ground for mosquitoes
  • Increases risk of malaria spread when near housing and settlements
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7
Q

SEF: Overcrowded living conditions

A
  • Large number of people clustered together in small area
  • Share same spaces and use same items
  • Interact with each other more often and closely = faster spread of diseases
  • Overcrowded and unhygienic rooms w/o proper ventilation speeds up rate at which humans get bitten
  • Nocturnal anopheles mosquitoes enter and spreads malaria
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8
Q

SEF: Limited provision and access to HC

A

> Limited HC
- Shortage of doctors, lack of health services and high costs of treatment increase spread of malaria
- Delayed treatment = increased time for spreading
- Caused by low investment in HC sector, govt funds concentrated elsewhere

e.g. India, highest number of malaria cases in Asia
- 6 doc per 10,000 patients
- 4% of GDP spent on HC

> Inaccessible treatment
- Artemisinin Combination Therapy (ACT) unaffordable in many poor places where malaria is prevalent
- Cannot afford = resort to cheaper/less effective treatments or no treatment at all
- Treatment over long term, financially draining

  • Partial/incomplete course of treatment may cause malaria parasite to develop resistance to drug, requiring more expensive medication to treat
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9
Q

EnvF: Poor drainage and stagnant waters

A
  • Creates favourable conditions for growth of mosquitoes
  • Low awareness, no precautions, mosquitoes breed quickly w/o interruption

e.g. Rajasthan canals, India
- Parts of the 800km long canals leaked, developing swamps serving as breeding grounds for anopheles mosquitoes
- Frequent malaria outbreaks in north-western india

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10
Q

EnvF: Effects of climate

A

> Temp
1) 22-33*c increases lifespan of mosquito
- Increases frequency of bites

2) High temps shorten development time of parasites in mosquito host
- Mosquitoes become infectious sooner

3) High temps decrease aquatic life cycle from 20 days to 7 days
- Mosquitoes become active sooner

> Rainfall
1) Poor drainage and evaporation create stagnant pools of water, providing breeding grounds

2) Monsoon seasons bring large amounts of rainfall
- Wash away breeding grounds, temporary decrease in malaria cases
- Pools form from heavy rains, stagnate, breed mosquitoes, spike in malaria cases weeks after monsoon season ends

> Relative Humidity
1) Ranges from 50%-60% needed for survival of mosquito
- High humidity increases lifespan of mosquito
- Able to infect more people

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11
Q

Impacts of malaria

A

> Social
1) Death rate
2) IMR

> Economic
1) Household burden
2) Cost of HC
3) Loss of productivity

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12
Q

SI: Death rates

A
  • 241 million cases of malaria in 2020
  • 630, 000 deaths from malaria in 2020
  • Africa was home to 95% of malaria cases and 96% of malaria deaths, 2020
  • Children under 5 accounted for about 80% of all malaria deaths in Africa, 2020
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13
Q

SI: IMR

A
  • Women who contract malaria during pregnancy may infect unborn child
  • Around 75,000 to 200,000 infants die within first year of birth due to malarial infection during pregnancy
  • May result in under-developed immune system
  • Immunocompromised may die from basic diseases
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14
Q

EI: Household burden

A
  • Increased medical expenses

e.g. Ghana, 34% of household income spent on HC

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15
Q

EI: Cost of HC

A
  • Countries affected by malaria needs to set aside funds for building, maintaining and investing in medical infra, purchase of medicine, equipment (i.e. insecticide treated nets)
  • e.g. Malaria accounts for 40% of public health spendings in some countries
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16
Q

EI: Loss of productivity

A
  • Unable to work due to poor health
  • Rate at which goods and services produced decreases
  • Earn lower income
  • Slows down economic growth

e.g. Africa, economy slows 1.3% every year due to malaria

17
Q

Reasons for re-emergence of Malaria

A

1) Resistance to anti-malarial drugs
2) Air Travel
3) Climate change
4) Insecticide-resistant mosquitoes

18
Q

Malarial parasites developing resistance to anti-malarial drugs

A
  • Rise in use of counterfeit or incomplete doses of anti-malarial drugs
  • Surviving malarial parasites build resistance to drugs

e.g. Indian migrant workers developed anti-malarial drug resistant parasites in Thailand, brought it back to india
- Existing malarial drug in India became ineffective against parasite
- Difficult to contain spread of malaria inside India

19
Q

Air travel causing re-emergence of malaria

A
  • Aids in relocation diffusion
  • Mosquitoes hide in plane/infected person travels

e.g. 1995, Malaria first reported in Southern France
- Cases occured in areas non-endemic to malaria and amongst people who had not travelled

20
Q

Climate Change resulting in re-emergence of malaria

A
  • Temp increase at higher latitudes and altitudes
  • More locations suitable for breeding mosquitoes

e.g. Central Highlands region of kenya warmer
- 4mil people at risk of malaria

21
Q

Insecticide-resistant mosquitoes resulting in re-emergence of malaria

A
  • Chemical pesticide DDT replaced by chemicals like pyrethroids
  • Some chemicals no longer effective against mosquitoes
  • Mosquitoes build resistance to insecticide in short time

e.g. Insecticide resistant mosquitoes detected in 64 countries

22
Q

Challenges in managing spread of malaria

A

> Socio-economic
1) Limitations of HC
2) Population movement due to efficient transport and communications
- Population movement
- Border control
- Travel advisories

> Environmental
1) Climate change
2) Effects of monsoons

23
Q

SEC: Limitations of HC

A
  • Ability of malaria parasites developing resistance to drugs
  • Caused by incomplete treatment of infected person
  • Failure to develop vaccine to provide immunity

e.g. Thai-Cambodia border, malarial drug resistant mosquitoes found

24
Q

SEC: Population movements due to efficient transport and communications

A

1) Population movements
- Movement of people along borders faster and on larger scales
- Spreads and transmits diseases to new locations
- Control and monitoring programmes ineffective since it is difficult to monitor movement of people

2) Border control
- Controls where large-scale population movement occurs
- Controls flow of goods and people across borders
- Malaria spreads with uncontrolled migration and lack of coordination between borders
- Malaria prevalent and spreads along international borders
to non-endemic regions

3) Travel advisories
- Official notices that inform travellers about specific risks of travelling to specific areas
- Issued by govt
- Proved useful in reducing travel to places where risk of infection is very high
- May not reach everyone (i.e. those w/o news / illiterate)

25
Q

EnvC: Climate change

A

> Increased temp
- Provides longer periods for mosquitoes to breed and spread malaria
- Mosquitoes breed and mature faster

> Increased rainfall
- More pools of stagnant water over large areas
- More breeding grounds

26
Q

EnvC: Effects of monsoons

A
  • High rainfall during wet seasons
  • Positive DELAYED relationship
  • Mosquitoes born w/o malaria parasite, time needed to contract and propogate parasite