Health across the lifecourse Flashcards

1
Q

What is the Barker hypothesis

A

Intrauterine growth retardation, low birth rate and premature birth have a causal relationship to the origins of hypertension, CHD and non insulin dependent diabetes in adulthood

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2
Q

What ideas underpin social epidemiology

A

Biological and psychosocial exposures in childhood lead to thigns in adulthood
eg air pollution, poor educational attainment–> rapid decline in lung functio

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3
Q

Name 3 birth cohort studies

A

Born in Bradford
ALSPAC
1946 birth experiment

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4
Q

Effect of DNA methylation on gene expression

A

Increased methylation turns genes off and vice versa

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