Health across the lifecourse Flashcards
1
Q
What is the Barker hypothesis
A
Intrauterine growth retardation, low birth rate and premature birth have a causal relationship to the origins of hypertension, CHD and non insulin dependent diabetes in adulthood
2
Q
What ideas underpin social epidemiology
A
Biological and psychosocial exposures in childhood lead to thigns in adulthood
eg air pollution, poor educational attainment–> rapid decline in lung functio
3
Q
Name 3 birth cohort studies
A
Born in Bradford
ALSPAC
1946 birth experiment
4
Q
Effect of DNA methylation on gene expression
A
Increased methylation turns genes off and vice versa