hallucinogens 1 Flashcards

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1
Q

what are hallucinogens?

A

drugs that induce hallucinations

  • induces an altered state of consciousness
  • altered state characterised by distortions of perception, hallucinations, visions
  • also known as psychedelics (mind revealing)
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2
Q

what are classical hallucinogens?

A
  • psilocybin (magic mushrooms)
  • LSD
  • agonists at serotonin receptors
  • primary effect = altered state of consciousness
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3
Q

what are dissociative anaesthetics?

A
  • synthetic drugs
  • such as PCP and ketamine
  • produce anaesthesia (loss of all sensation) at higher doses
  • alter states of consciousness at lower doses
  • induces state of disconnection from environment (loss of time) and body (altered perception of body consistency, out of body experience)
  • non-competitive NDMA receptor antagonists
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4
Q

compare classical hallucinogens and dissociative anaesthetics

A
  • researcher had ppts complete questionnaire with 5 primary dimension to measure difference
  • oceanic boundlessness - referring to positive experienced loss of ego boundaries
  • anxious ego-disintegration - thought disorder and loss of self-control
  • visionary restructuralization - referring to alterations of perception
  • acoustic alterations - hypersensitivity to sound and auditory hallucinations
  • in classical hallucinogens, tend to score higher in visionary restructuralization
  • in dissociative anaesthetics, tend to score higher in anxious ego-disintegration
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5
Q

what are hallucinogen effects heavily dependent on?

A
  • user’s expectations (set)
  • environment of user (setting)
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6
Q

what did Stanislov Grof (1975) state about LSD and hallucinogenic drugs?

A
  • considers LSD to be powerful drug
  • it amplifies biochemical and physiological processes in the brain
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7
Q

what did Barr et al. (1972) state about LSD and hallucinogenic drugs?

A
  • the phenomena induced by LSD cannot be predicted or understood in pharmacological terms
  • personality of drug taker plays critical role in determining how much effect there will be
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8
Q

what have natural hallucinogens been used for?

A
  • often used as part of rituals
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9
Q

what was PCP developed as in mid 1950’s?

A

anaesthetic

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10
Q

what is used as an anaesthetic today in humans?

A
  • synthesised ketamine
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11
Q

what was ketamine approved as a treatment for?

A

as treatment for depression in the US (2019)

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12
Q

what is Ecstasy?

A
  • MDMA
  • amphetamine
  • strong effects of serotonin transmission
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13
Q

identify properties of ecstasy

A
  • stimulant properties
  • increasing alertness and energy
  • increases hallucinogenic-like properties
  • increases sociability
  • has high oceanic boundlessness
  • has low visionary restructualization
  • has low ego-dissolution
  • weaker alteration of consciousness compared to LSD
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14
Q

what is the proportion of 16-59 year olds using LSD?

A

0.4%

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15
Q

what is the proportion of 16-59 year olds using magic mushrooms?

A

0.4%

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16
Q

what is the proportion of 16-59 year olds using ketamine?

A

0.8%

17
Q

in global drug survey (2017) what ranking is MDMA/ecstasy?

A

ranks second (after cannabis)

18
Q

what did David Nutt say was more dangerous than ecstasy?

A

horse-riding was less dangerous than ecstasy

19
Q

what harm can classical hallucinogenic drugs cause?

A
  • depends on the set and the setting
  • these drugs otherwise cause no physical harm
  • these drugs don’t cause dependence
20
Q

what harm can ecstasy and dissociative anaesthetics (PCP, ketamine) cause?

A
  • dependence
  • neurodegeneration
21
Q

how many ecstasy-related deaths in England?

A

about 130

22
Q

how many drug classes are there?

A
  • 3
  • A, B, C

these determine the penalties for offences (supply, production, possession)

23
Q

what class and schedule is ketamine?

A
  • class C
  • schedule 4
24
Q

what class and schedule is LSD?

A
  • class A
  • schedule 1
25
Q

what class and schedule is MDMA?

A
  • class A
  • schedule 1
26
Q

what class and schedule is psilocybin?

A
  • class A
  • schedule 1
27
Q

what are the 5 schedules?

A
  • schedules regulate the clinical use of controlled substances
  • regulate their storage and labelling requirements