HAEMOSTASIS Flashcards

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1
Q

WHAT ARE THE THREE STEPS OF HAEMOSTASIS

A

VASCULAR SPASM
PLATELET PLUG FORMATION
COAGULATION

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2
Q

WHAT IS HAEMOSTASIS

A

A FAST SERIES OF REACTIONS FOR STOPPAGE OF BLEEDING

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3
Q

WHAT IS INVOLVED IN TEH VASCULAR SPASM OF HAEMOSTASIS

A

SMOOTH MUSCLE CONTRACTS CAUSING VASOCONSTRICTION

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4
Q

WHAT IS INVOLVED IN TH EPLATELET PLUG FORMATION OF HAEMOSTASIS

A

INJURY OF LINING EXPOSES COLLAGEN FIBRES AND PLATELETS ADHERE

PLATLETS RELEASE CHAMICALS THAT MAKE THEM STICKY TO FORM A PLATELET PLUG

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5
Q

WHAT IS INVOLVED IN COAGULATION OF HAEMOSTASIS

A

FIBRIN FORMS A MESH THAT TRAPS RBC’s FORMING THE CLOT

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6
Q

VASCULAR SPASM IS MOST EFFECTIVE IN ____ BLOOD VESSELS

A

SMALL

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7
Q

WHAT FACTOR HELPS TO STABILISE PLATELET-COLLEGEN ADHESION

A

VON WILLEBRAND FACTOR

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8
Q

WHAT TWO MOLECULES ENHANCE VASCULAR SPASM AND PLATELET AGGREGATION

A

SEROTONIN
THROMBOXANE A2

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9
Q

BLOOD CLOTS ARE EFFECTIVE IN SEALING ____ BLOOD VESSELS

A

LARGE

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10
Q

WHAT TYPE OF INJURY CAUSES THE INTRINSIC PATHWAY CASCADE IN COAGULATION

A

INJURY FROM WITHIN THE BLOOD VESSEL

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11
Q

WHAT TYPE ON INJURY CAUSES THE EXTRINSIC PATHWAY CASCADE IN COAGULATION

A

INJURY TO TISSUES SURROUNDING THE VESSEL

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12
Q

IS TEH EXTRINSIC OR INTRINSIC PATHWAY OF COAGULATION FASTER

A

EXTRINSIC = BYPASSES SEVERAL STEPS

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13
Q

WHAT MOLECULE COVERTS PROTHROMBIN TO THROMBIN

A

BROTHROMBINASE

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14
Q

WHAT CONVERTS FINRINOGEN TO FIBRIN

A

THROMBIN

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15
Q

_____ STRANDS FORM THE STRUCTURAL BASIS OF A CLOT

A

FIBRIN

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16
Q

WHAT IS FIBRINOLYSIS

A

THE PROCESS THAT REMOVES THE CLOT

17
Q

WHAT ENZYME DIGESTS FIBRIN

A

PLASMIN

18
Q

WHEN DOES FIBRINOLYSIS BEGIN

A

WITHIN TWO DAYS OF A CLOR FORMING AND EXTENDS OVER A FEW DAYS UNTIL THE CLOT IS DISSOLVED

19
Q

WHAT ARE THE TWO CATEGORIES OF DISORDERS THAT AFFECT COAGULATION

A

UNDESIREABLE CLOTTING
BLOOD DISORDERS

20
Q

WHAT ARE TWO TYPES OF UNDESIREABLE CLOTTING

A

THROMBUS
THROMBOEMBOLISM

21
Q

WHAT ARE TWO TYPES OF LOOD DISORDERS

A

THROMBOCYTOPENIA
HAEMOPHILIA