haemodynamic dysfunction Flashcards

1
Q

define haemodynamic

A

factors that govern blood flow that are dependent on the relationship between cardiac output, blood pressure and resistance

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2
Q

cardiac out put = ?

A

heart rate X stroke volume

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3
Q

what is frank starling law

A

heart pumps more blood when its filled with more blood
more blood = stronger heart contraction = more blood out

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4
Q

what is oedema

A

accumulation of fluid in interstitial space

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5
Q

factors affecting intravascular and interstitial water movement

A

increased hydrostatic pressure
lymphatic obstruction
inflammation
decreased blood volume

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6
Q

when does fluid accumulate

A

if movement of water in tissues exceeds lymphatic drainage

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7
Q

what is hyperaemia

A

localised increased volume of oxygenated blood
an active process resulting from arteriole dilation

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8
Q

what does hyperaemia help with

A

removal of waste materials and dilution of harmful substances by bringing more fluid and antibodies to area

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9
Q

what is congestion

A

passive process resulting from impaired outflow from a tissue

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10
Q

2 types of congestion

A

systematic - cardiac failure
local - isolated venous obstruction

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11
Q

differences of hyperaemia and congestion

A

H = active C = passive
H = increased blood flow C = impaired blood flow
H during exercise/inflammation C venous obstruction and cardiac failure
H = oxygenated blood / redder C = de oxygnated / blue

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12
Q

what is left sided heart failure

A

chronic congestion of lung

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13
Q

aetiology of left sided heart failure

A

systematic HT
valve disease
primary myocardial disease

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14
Q

clinical presentation of L sided

A

pulmonary congestion
oedema
salt and water retention = coma
brown lung

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15
Q

what is right sided heart failure

A

caused by L sided
pulmonary congestion and raised arterial pressure

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16
Q

clinical presentation of right sided

A

congestion and oedema peripherally
effusions in pleura
ascites of peritoneum
splenomegaly - enlarged

17
Q

what is haemostasis

A

blood clots at site of injury

18
Q

what are platelets

A

helps with clot formation
activates clotting cascade

19
Q

what is a haemorrhage

A

bleeding from a damaged blood vessel

20
Q

six stages of clot formation

A

vasoconstriction
platelet
coagulation
formation of final clot
clot removal - normal blood flow

21
Q

define thrombosis

A

blood clots at site of vascular injury

22
Q

3 components of thrombosis

A

vascular wall
platelets
coagulation failure

23
Q

what does Virchow’s triad say causes thrombus formation

A

endothelial injury
stasis of blood
blood hyper coagulability

24
Q

what is the endothelium

A

thin layer of cells on the interior surface of blood, lymphatic vessels and heart

25
Q

endothelial dysfunction is the key factor in which diseases

A

atherosclerosis
hypertension
diabetes- vascular complications
heart attack and stroke

26
Q

what is propagation

A

additional platelets and fibrin accumulate

27
Q

what is embolization

A

thrombi dislodges and travels through blood

28
Q

what is an embolism

A

dislodged thrombi

29
Q

what is ischaemic necrosis

A

death of tissue resulting from lack of blood supply

30
Q

what is myocardial infarction

A

death of heart muscle due to blocked coronary arteries

31
Q

what is hypoxemia

A

low level of oxygen in blood specifically arterial blood

32
Q

what are most infarcts replaced by

A

scar tissue