Haematology - biochem* Flashcards
life span of mature RBCs
120 days
where are new RBCs produced
red bone marrow
where do old RBCs go
phagocytic cells of the liver and spleen engulf old RBCs
globular haemoglobin proteins are broken down into amino acids which enter the blood stream
Ham group minus the iron is converted into bilirubin which is transported to the liver
iron binds to transferrin in the blood and is recycled
size of a mature erythrocyte
8 mini m in dm
2 thick at edge
1 thick in centre
why is is shaped like a concave
diffusion distance maximised
surface to volume ratio maximised
flexible membrane can deform to allow cells to squeeze in single file through capillaries
percentage of RBCS in whole of blood is called what
haemocrit
when fully saturated how much oxygen does 1g of Hb bind
1.34 ml of oxygen
normal adult concentrations
males 130-180
females 115-165
what is the difference between fetal hb and adult hb
fetal hb has a high affinity for oxygen than adult hb does
