Haematology Flashcards

1
Q

What is the presentation for CML?

A

Splenomegaly, FLAWS, Philadelphia chromosome

Treatment: Imatinib

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2
Q

What is the presentation for vWD?

A

Menorrhagia, abnormal bleeding, excess post-op bleeding, decreased factor 8, normal PT, increased APTT

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3
Q

What is the test for SLE?

A

Spherocytes, reticulocytosis

Warm auto-immune haemolytic anaemia (Coomb’s test)

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4
Q

What is seen in thrombocytosis?

A

Splenomegaly, dusky discolouration of hands, thrombosis, bleeding, headache, dizziness

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5
Q

What is seen in haemolytic anaemia?

A

Low Hb, high bilirubin, Heinz bodies and bite cells

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6
Q

How does DIC act?

A

Increased coagulation, widespread clot formation, tissue ischaemia, then increased bleeding
Triggered by sepsis, increased D-dimer

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7
Q

What is the treatment for autoimmune haemolytic anaemia?

A

Corticosteroids

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8
Q

What is the treatment for vWD?

A

Desmopressin

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9
Q

What type of anaemia explains opthalmoplegia, ataxia and confusion?

A

Wernicke’s encephalopathy (thiamine deficiency), siderblastic anaemia (macrocytic) due to excess alcohol

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