Haematology Flashcards
What is the presentation for CML?
Splenomegaly, FLAWS, Philadelphia chromosome
Treatment: Imatinib
What is the presentation for vWD?
Menorrhagia, abnormal bleeding, excess post-op bleeding, decreased factor 8, normal PT, increased APTT
What is the test for SLE?
Spherocytes, reticulocytosis
Warm auto-immune haemolytic anaemia (Coomb’s test)
What is seen in thrombocytosis?
Splenomegaly, dusky discolouration of hands, thrombosis, bleeding, headache, dizziness
What is seen in haemolytic anaemia?
Low Hb, high bilirubin, Heinz bodies and bite cells
How does DIC act?
Increased coagulation, widespread clot formation, tissue ischaemia, then increased bleeding
Triggered by sepsis, increased D-dimer
What is the treatment for autoimmune haemolytic anaemia?
Corticosteroids
What is the treatment for vWD?
Desmopressin
What type of anaemia explains opthalmoplegia, ataxia and confusion?
Wernicke’s encephalopathy (thiamine deficiency), siderblastic anaemia (macrocytic) due to excess alcohol