Haematology Flashcards
Anti thrombin new anticoagulants
Dabigatran
Drug used in primary haemostatic disorders?
Tranexamic acid
Anti Xa new anticoagulants?
Rivaroxiban, apixuban
Side effects of heparin
Heparin induced thrombocytopenia, hypoaldosteronism & hyperkalaemia, hypersensitivity
A synthetic pentasaccharide that has anti Xa activity, used in the prophylaxis and treatment of thrombo-embolic disease, unstable angina and STEMI via SC injection
Fondaparinux
Anti thrombin agent taken from leaches
Hirudins
Mixture of glycosaminoglycans, anticoagulant, anti Xa and anti-thrombin activity, can cross react with HIT antibodies
Danaparoid
Vitamin K antagonists
Warfarin, acenocoumarol, phenindione
How does dabigatran work?
A tran is an anti thrombin agent
How does rivaroxaban, apixaban work?
Xaban is an anti Xa agent