Depression Flashcards
0
Q
Examples of TCA’s?
A
Amitriptyline, Imipramine, nortryptiline, clomipramine
1
Q
How do TCA’s work?
A
Inhibit reuptake of serotonin and noradrenaline (have effects on Ach and histamine receptors aswell)
2
Q
Adverse effects of TCA’s?
A
Sedation, confusion, motor inco-ordination, weight gain, atropine like (antimuscarinic), dangerous in overdose due to cardiac arrythmias due to alpha 1 blockage
3
Q
Contraindications to TCA’s?
A
Recent MI, narrow angle glaucoma, prostatism, heart block
4
Q
Examples of mono amine oxidase inhibitors
A
Phenelzine, isocarboxazid, tranylcypromine, moclibemide