Depression Flashcards

0
Q

Examples of TCA’s?

A

Amitriptyline, Imipramine, nortryptiline, clomipramine

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1
Q

How do TCA’s work?

A

Inhibit reuptake of serotonin and noradrenaline (have effects on Ach and histamine receptors aswell)

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2
Q

Adverse effects of TCA’s?

A

Sedation, confusion, motor inco-ordination, weight gain, atropine like (antimuscarinic), dangerous in overdose due to cardiac arrythmias due to alpha 1 blockage

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3
Q

Contraindications to TCA’s?

A

Recent MI, narrow angle glaucoma, prostatism, heart block

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4
Q

Examples of mono amine oxidase inhibitors

A

Phenelzine, isocarboxazid, tranylcypromine, moclibemide

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